Evidence map›Paper›PMID 31019904›Full record

ArticleFrontiers in pediatrics2019

Massive Amniotic Fluid Aspiration in a Case of Sudden Neonatal Death With Severe Hypoplasia of the Retrotrapezoid/Parafacial Respiratory Group.

Anna M Lavezzi, Antonella Poloniato, Rosanna Rovelli, Laura Lorioli, Gabriela Alejandra Iasi, Teresa Pusiol, Graziano Barera, Stefano Ferrero

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Anna M LavezziDepartment of Biomedical, Surgical and Dental Sciences, Lino Rossi Research Center for the Study and Prevention of Unexpected Perinatal Death and SIDS, University of Milan, Milan, Italy.
Antonella PoloniatoNeonatal Unit, IRCCS Ospedale San Raffaele, Milan, Italy.
Rosanna RovelliNeonatal Unit, IRCCS Ospedale San Raffaele, Milan, Italy.
Laura LorioliNeonatal Unit, IRCCS Ospedale San Raffaele, Milan, Italy.
Gabriela Alejandra IasiPathology Unit, IRCCS Ospedale San Raffaele, Milan, Italy.
Teresa PusiolInstitute of Pathology, Hospital of Rovereto, Rovereto, Italy.
Graziano BareraNeonatal Unit, IRCCS Ospedale San Raffaele, Milan, Italy.
Stefano FerreroDepartment of Biomedical, Surgical and Dental Sciences, Lino Rossi Research Center for the Study and Prevention of Unexpected Perinatal Death and SIDS, University of Milan, Milan, Italy.
IRCCS Ospedale San Raffaele · ITCenter for Neuroscience and Cognitive Systems · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of a baby, who, after pregnancy complicated by maternal Addison's disease and Hashimoto's thyroiditis and natural delivery, unexpectedly presented a cardiorespiratory collapse and died 1 hour after birth without responding to prolonged neonatal resuscitation maneuvers. The cause of death was reliably established by carrying out a forensic postmortem examination. More specifically, the histological examination of the lungs showed the presence of abundant endoalveolar and endobronchial cornea scales caused by absorption of amniotic fluid. The neuropathological examination of the brainstem highlighted severe hypodevelopment of the retrotrapezoid/parafacial respiratory group, which is a complex of neurons located in the caudal pons that is involved in respiratory rhythm coordination, especially expiration, in conditions of enhanced respiratory drive, as well as in chemoreception. This neuropathological finding shed new light on the mechanisms underlying the massive amniotic fluid aspiration which led to this early death.

Indexed as

amniotic fluid inhalationbrainstemhypoplasianewbornretrotrapezoid/parafacial respiratory groupsudden neonatal death

Identifiers

PMID31019904
PMCPMC6458245
OpenAlexW2928767037

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.