Evidence map›Paper›PMID 31019837›Full record

ArticleTurkish journal of obstetrics and gynecology2019

Cost-effectiveness of GnRH antagonist implementation on hCG injection day.

Ayşe Zehra Özdemir, Bülent Ayas, Davut Güven, Aysın Pınar Türkmen, Çağrı Gülümser

Abstract read
In one paragraph

Article in Turkish journal of obstetrics and gynecology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ayşe Zehra ÖzdemirOndokuz Mayıs University Hospital, In vitro Fertilisation Center, Samsun, Turkey.ORCID https://orcid.org/0000-0003-4232-4794
Bülent AyasOndokuz Mayıs University Hospital, In vitro Fertilisation Center, Samsun, Turkey.ORCID https://orcid.org/0000-0003-4411-2496
Davut GüvenOndokuz Mayıs University Hospital, In vitro Fertilisation Center, Samsun, Turkey.ORCID https://orcid.org/0000-0001-8587-0707
Aysın Pınar TürkmenOndokuz Mayıs University Hospital, In vitro Fertilisation Center, Samsun, Turkey.ORCID https://orcid.org/0000-0003-0330-9655
Çağrı GülümserUniversity of Health Science, Department of Obstetrics and Gynecology, İstanbul, Turkey.ORCID https://orcid.org/0000-0002-4066-9038

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the outcomes of antagonist stimulation protocols and to compare the cost effectiveness. MATERIALS AND

methodsBetween 2011 and December 2017, a total of 354 women who underwent intracytoplasmic sperm injection and controlled ovarian stimulation with antagonist protocols were enrolled in the study. The antagonist implementation on the day of human chorionic gonadotropin (hCG) was continued for 194 of women, whereas the antagonist was stopped 36 hours before in 160 women. The stimulation outcomes of patients and cost-effectiveness of the regimens were compared.

resultsThere was a significant difference between the groups in terms of number of cryopreserved embryos, mature/immature oocyte ratio, and embryo transfer cancellations (p<0.05). The median value for the mature/immature oocyte ratio was 1.1 (0.2-7.5) and 1 (0.5-15) (p=0.001), and the ET cancellation was 5.3% vs. 1% for group 1 and 2, respectively (p=0.037). There was no difference between the groups in terms of pregnancy rates (p=0.197).

conclusionNo difference was found in the clinical pregnancy rates between the two groups. For this reason, the cessation of antagonist implementation on the day of hCG seems more advantageous in terms of cost-effectiveness and fewer injections.

Indexed as

Controlled ovarian stimulationcost effectivenesspregnancy rates

Identifiers

PMID31019837
PMCPMC6463428

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.