Evidence map›Paper›PMID 31019725›Full record

ArticleMultiple sclerosis journal - experimental, translational and clinical

Predictors of hospital-based multidisciplinary rehabilitation effects in persons with multiple sclerosis: a large-scale, single-centre study.

Elisabetta Groppo, Alessio Signori, Maria Pia Sormani, Cristina Grosso, Loredana La Mantia, Davide Cattaneo, Marco Rovaris

Open access · goldAbstract read
In one paragraph

Article in Multiple sclerosis journal - experimental, translational and clinical. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  3. Sex-Specific Effects ofInternational journal of molecular sciences · 2025
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  9. Rehabilitation in atypical neurological disease: a case report.The Journal of international medical research · 2022
    Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Elisabetta GroppoMultiple Sclerosis Center and Neurorehabilitation Unit, IRCCS Fondazione Don Gnocchi, Italy.
Alessio SignoriDepartment of Health Sciences (DISSAL), University of Genoa, Italy.
Maria Pia SormaniDepartment of Health Sciences (DISSAL), University of Genoa, Italy.ORCID https://orcid.org/0000-0001-6892-104X
Cristina GrossoMultiple Sclerosis Center and Neurorehabilitation Unit, IRCCS Fondazione Don Gnocchi, Italy.
Loredana La MantiaMultiple Sclerosis Center and Neurorehabilitation Unit, IRCCS Fondazione Don Gnocchi, Italy.
Davide CattaneoLaRICE Research Laboratory, IRCCS Fondazione Don Gnocchi, Italy.
Marco RovarisMultiple Sclerosis Center and Neurorehabilitation Unit, IRCCS Fondazione Don Gnocchi, Italy.ORCID https://orcid.org/0000-0001-9691-1957
Don Carlo Gnocchi Foundation · ITUniversity of Genoa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPersons with multiple sclerosis may benefit from hospital-based multidisciplinary rehabilitation.

objectivesTo investigate the effects of hospital-based multidisciplinary rehabilitation and to identify their potential predictors in a large sample of persons with multiple sclerosis.

methodsFrom the charts of 655 persons with multiple sclerosis consecutively admitted to our unit, disease profiles, modified Barthel index, Expanded Disability Status Scale (EDSS), pain numerical rating score and type of interventions were retrospectively collected. We defined an improvement at discharge as follows: modified Barthel index increase of at least 5 points, EDSS decrease of 1.0 if baseline score was 5.5 or less and of 0.5 if baseline score was greater than 5.5; any numerical rating score decrease.

resultsAfter a median admission period of 36 days, at discharge 65%, 22% and 89% of persons with multiple sclerosis improved for modified Barthel index, EDSS and numerical rating score, respectively. The modified Barthel index improvement was associated with shorter disease duration, lower EDSS at baseline and with access to psychological counselling. EDSS improvement was associated with shorter disease duration, relapsing-remitting course, female gender and longer duration of the admission period.

conclusionsInpatient multidisciplinary rehabilitation was associated with improved autonomy in activities of daily living in a relevant proportion of persons with multiple sclerosis. The effect seems to be more evident in individuals with shorter multiple sclerosis duration and relapsing-remitting disease course.

Indexed as

inpatient settingMultidisciplinary rehabilitationmultiple sclerosis

Identifiers

PMID31019725
PMCPMC6469285
OpenAlexW2939824427

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.