ReviewDigital health
Efficacy of mobile application interventions for the treatment of post-traumatic stress disorder: A systematic review.
Review in Digital health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 4 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- Effects of mhealth applications on military personnel's physical and mental health: A systematic review.Military psychology : the official journal of the Division of Military Psychology, American Psychological Association · 2025Pooled it
- Digital-Based Interventions for Complex Post-Traumatic Stress Disorder: A Systematic Literature Review.Trauma, violence & abuse · 2024Pooled it
- Computerized Cognitive Behavioral Therapy for Treatment of Depression and Anxiety in Adolescents: Systematic Review and Meta-analysis.Journal of medical Internet research · 2022Pooled it
- Efficacy of Self-Management Smartphone-Based Apps for Post-traumatic Stress Disorder Symptoms: A Systematic Review and Meta-Analysis.Frontiers in neuroscience · 2020Pooled it
- Cost-Effectiveness of App-Guided Self-Management for Posttraumatic Stress: Trial-Based Economic Evaluation.Journal of medical Internet research · 2025Trial
- Brief Peer-Supported Web-Based Skills Training in Affective and Interpersonal Regulation (BPS webSTAIR) for Trauma-Exposed Veterans in the Community: Randomized Controlled Trial.Journal of medical Internet research · 2024Trial
- The Impact of User Engagement With Exposure Components on Posttraumatic Stress Symptoms in an mHealth Mobile App: Secondary Analysis of a Randomized Controlled Trial.JMIR mHealth and uHealth · 2024Trial
- Efficacy, Benefits, and Harms of a Self-management App in a Swedish Trauma-Exposed Community Sample (PTSD Coach): Randomized Controlled Trial.Journal of medical Internet research · 2022Trial
- A Self-Help App for Syrian Refugees With Posttraumatic Stress (Sanadak): Randomized Controlled Trial.JMIR mHealth and uHealth · 2021Trial
- The Development and Protocol for Testing a Co-Created Digital Intervention (Sentinel) to Improve Mental Well-Being and Help Manage and Prevent Trauma in First Responders.JMIR research protocols · 2026Article
- PTSD and complex PTSD, current treatments and debates: a review of reviews.British medical bulletin · 2025Review
- Using Passive and Active Data to Predict Post-Traumatic Stress Disorder Symptoms and Cannabis Use in Recently Discharged UK Veterans: A Protocol for the MAVERICK Feasibility Study.Mental health science · 2024Article
- Article
- Integration of a smartphone app with posttraumatic stress disorder treatment for frontline workers: a pilot study.Australian journal of psychology · 2024Article
- Digital Therapeutic Intervention for Women in the UK Armed Forces Who Consume Alcohol at a Hazardous or Harmful Level: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2023Article
- An umbrella review of effectiveness and efficacy trials for app-based health interventions.NPJ digital medicine · 2023Review
- Mobile Health Interventions to Improve Health Behaviors and Healthcare Services among Vietnamese Individuals: A Systematic Review.Healthcare (Basel, Switzerland) · 2023Review
- Longitudinal follow-up of the randomized controlled trial of access to the trauma-focused self-management app PTSD Coach.Internet interventions · 2023Article
- Cognitive reappraisal in mHealth interventions to foster mental health in adults: a systematic review and meta-analysis.Frontiers in digital health · 2023Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMany adults with post-traumatic stress disorder (PTSD) are unable to access healthcare services for treatment due to logistical, social, and attitudinal barriers. Interventions delivered via mobile applications (apps) may help overcome these barriers.
objectiveThe aim of this study is to systematically evaluate the most recent evidence from trials investigating the efficacy of mobile apps for treating PTSD.
methodsPubMed, Web of Science, Embase, PsycINFO, and Medline were searched in February 2018. Randomised controlled trials (RCTs) were included if they quantitatively evaluated the efficacy of a mobile app for treating PTSD as part of the primary aim. Findings were presented in a narrative synthesis.
resultsIn the five identified RCTs, the use of app-based interventions appeared to be associated with reductions in PTSD symptoms. However, the strength of evidence for this association appeared to be inconsistent, and there was little evidence that those using the apps experienced greater reductions in PTSD symptoms than those in control conditions. Nonetheless, there was some evidence that app-based interventions are both a feasible and acceptable treatment pathway option.
conclusionsIncluded studies were often limited by small sample sizes, brief intervention, and follow-up periods, and self-reported measures of PTSD. Evidence for the efficacy of mobile interventions for treating PTSD was inconclusive, but promising. Healthcare professionals should exercise caution in recommending app-based interventions until the potentially adverse effects of app use are better understood and larger-scale studies have taken place.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.