Observational studyUnited European gastroenterology journal2019
Combined excision and ablation of ampullary tumors with biliary or pancreatic intraductal extension is effective even in malignant neoplasms.
Observational study in United European gastroenterology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Therapeutic strategies and outcomes in the management of ampullary tumours: meta-analysis.BJS open · 2026Pooled it
- A sequential strategy of upfront radiofrequency ablation followed by endoscopic papillectomy for complex ampullary tumors.Frontiers in medicine · 2026Article
- Safety of intrabiliary radiofrequency ablation in cases of residual and recurrent neoplasia after endoscopic papillectomy.Endoscopy international open · 2025Review
- Organ and function preservation in gastrointestinal cancer: Current and future perspectives on endoscopic ablation.World journal of gastrointestinal endoscopy · 2024Article
- New Method of Papillectomy May Decrease Recurrence: Anchoring Method versus Conventional Method.Journal of clinical medicine · 2024Article
- Updates on the Management of Ampullary Neoplastic Lesions.Diagnostics (Basel, Switzerland) · 2023Review
- Long-term follow-up of endoscopic papillectomy and the value of preventive pancreatic stent placement (with videos).Gastroenterology report · 2023Article
- Role of Endoscopy in Management of Upper Gastrointestinal Cancers.Diseases (Basel, Switzerland) · 2022Review
- Efficacy and safety of endoscopic papillectomy: a multicenter, retrospective, cohort study on 227 patients.Therapeutic advances in gastroenterology · 2022Article
- Endoscopic papillectomy for ampullary adenomatous lesions: A literature review.World journal of gastrointestinal oncology · 2021Review
- Radiofrequency ablation for intraductal extension of ampullary adenomatous lesions: proposal for a standardized protocol.Endoscopy international open · 2021Article
- Systematic Review with Meta-Analysis: Endoscopic and Surgical Resection for Ampullary Lesions.Journal of clinical medicine · 2020Review
- Novel endoscopic papillectomy for reducing postoperative adverse events (with videos).World journal of gastroenterology · 2020Article
- Synchronous Periampullary Tumors in a Patient With Pancreas Divisum and Neurofibromatosis Type 1.Frontiers in genetics · 2020Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The feasibility and outcome of endoscopic resection in ampullary tumors with intraductal growth remains unclear. Objective: To assess the safety, feasibility and outcomes of these patients treated by thermal ablation. Methods: Retrospective observational study. All consecutive patients who underwent an endoscopic snare papillectomy with a 6-month minimum follow-up were included. Ablation was performed with cystotomes and soft/forced coagulation. Successful endoscopic treatment was defined as no adenomatous residual tissue or recurrence observed at follow-up. Results: Of 86 patients presenting with an ampullary tumor, 73 (58 ± 14 years old, 49% men, 34% familial adenomatous polyposis) (median tumor size: 20 mm, range: 8-80) were included. En bloc and curative resection rates were achieved in 46.6% and 83.6%, respectively.Intraductal ingrowth was seen in 18 (24.7%) patients and histologically confirmed in 12 (16.4%). Intraductal ablation achieved a 100% success rate, with a 20-month median follow-up. Most of these patients had malignant forms ( Conclusions: Intraductal ablation achieves a high therapeutic success rate in ampullary tumors with ≤20 mm ductal extension, even in malignant forms or biliary and pancreatic involvement. The technique is feasible, cheap and safe and may avoid major surgery.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.