Evidence map›Paper›PMID 31019652›Full record

ArticleOxidative medicine and cellular longevity2019

DNA Methylation of miR-122 Aggravates Oxidative Stress in Colitis Targeting SELENBP1 Partially by p65NF-

Jianan Bai, Junchi Yu, Jintian Wang, Bingyan Xue, Na He, Ye Tian, Lixia Yang, Yipin Wang, Yanyan Wang, Qiyun Tang

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  4. Shikonin attenuates HExperimental and therapeutic medicine · 2021
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jianan BaiThe First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0001-7822-7297
Junchi YuThe Third Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Jintian WangThe First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Bingyan XueThe First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Na HeThe First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Ye TianThe First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Lixia YangPeople's Hospital of Linyi County, Dezhou, China.
Yipin WangThe Affiliated Sir Run Run Hospital of Nanjing Medical University, Nanjing, China.
Yanyan WangThe Affiliated Sir Run Run Hospital of Nanjing Medical University, Nanjing, China.
Qiyun TangThe First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0002-8354-5406
Jiangsu Province Hospital · CNNanjing Medical University · CNNanjing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aberrant microRNA (miRNA) expressions contribute to the development and progression of various diseases, including Crohn's disease (CD). However, the accurate mechanisms of miRNAs in CD are definitely unclear. We employed colonic tissue samples from normal volunteers and CD patients, an acute mice colitis model induced by 2,4,6-trinitro-benzene-sulfonic acid (TNBS), and a cellular oxidative stress model induced by H

Indexed as

AnimalsBase SequenceColitisCrohn DiseaseDNA MethylationDown-RegulationHT29 CellsHumansHydrogen PeroxideMiceMicroRNAsOxidative StressSelenium-Binding ProteinsSignal TransductionTrinitrobenzenesulfonic AcidHydrogen PeroxideMicroRNAsMIRN122 microRNA, humanMirn122 microRNA, mouseSELENBP1 protein, humanSelenbp1 protein, mouseSelenium-Binding ProteinsTrinitrobenzenesulfonic Acid

Identifiers

PMID31019652
PMCPMC6451819
OpenAlexW2923540596

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.