Evidence map›Paper›PMID 31019510›Full record

ArticleFrontiers in immunology2019

Performance of an Ultra-Sensitive Assay Targeting the Circulating Anodic Antigen (CAA) for Detection of

Mariana Silva Sousa, Govert J van Dam, Marta Cristhiany Cunha Pinheiro, Claudia J de Dood, Jose Mauro Peralta, Regina Helena Saramago Peralta, Elizabeth de Francesco Daher, Paul L A M Corstjens, Fernando Schemelzer Moraes Bezerra

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Research square · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Detecting twoFrontiers in parasitology · 2024
    Article
  17. Article
  18. Reproducibility matters: intra- and inter-sample variation of the point-of-care circulating cathodic antigen test in twoPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Article
  19. Schistosomiasis in non-endemic areas: Italian consensus recommendations for screening, diagnosis and management by the Italian Society of Tropical Medicine and Global Health (SIMET), endorsed by the Committee for the Study of Parasitology of the Italian Association of Clinical Microbiologists (CoSP-AMCLI), the Italian Society of Parasitology (SoIPa), the Italian Society of Gastroenterology and Digestive Endoscopy (SIGE), the Italian Society of Gynaecology and Obstetrics (SIGO), the Italian Society of Colposcopy and Cervico-Vaginal Pathology (SICPCV), the Italian Society of General Medicine and Primary Care (SIMG), the Italian Society of Infectious and Tropical Diseases (SIMIT), the Italian Society of Pediatrics (SIP), the Italian Society of Paediatric Infectious Diseases (SITIP), the Italian Society of Urology (SIU).Infection · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Mariana Silva SousaMedical Sciences Post Graduate Program, Department of Internal Medicine, School of Medicine, Federal University of Ceará, Fortaleza, Brazil.
Govert J van DamDepartment of Parasitology, Leiden University Medical Center, Leiden, Netherlands.
Marta Cristhiany Cunha PinheiroParasitology and Mollusks Biology Research Laboratory, Department of Clinical Analysis and Toxicology, Federal University of Ceará, Fortaleza, Brazil.
Claudia J de DoodDepartment of Cell and Chemical Biology, Leiden University Medical Center, Leiden, Netherlands.
Jose Mauro PeraltaDepartment of Immunology, Institute of Microbiology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Regina Helena Saramago PeraltaDepartment of Pathology, Fluminense Federal University, Niterói, Brazil.
Elizabeth de Francesco DaherMedical Sciences Post Graduate Program, Department of Internal Medicine, School of Medicine, Federal University of Ceará, Fortaleza, Brazil.
Paul L A M CorstjensDepartment of Cell and Chemical Biology, Leiden University Medical Center, Leiden, Netherlands.
Fernando Schemelzer Moraes BezerraMedical Sciences Post Graduate Program, Department of Internal Medicine, School of Medicine, Federal University of Ceará, Fortaleza, Brazil.
Universidade Federal do Ceará · BRLeiden University Medical Center · NLUniversidade Federal do Rio de Janeiro · BRUniversidade Federal Fluminense · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Techniques with high sensitivity and specificity are required for an accurate diagnosis in low-transmission settings, where the conventional parasitological methods are insensitive. We determined the accuracy of an up-converting phosphor-lateral flow circulating anodic antigen (UCP-LF CAA) assay in urine and serum for

Indexed as

Immunologic TestsAdolescentAdultAgedAnimalsAntigens, HelminthBrazilChildChild, PreschoolHumansLongitudinal StudiesMiddle AgedPopulation SurveillancePrevalenceReproducibility of ResultsSchistosoma mansoniAntigens, HelminthBrazilcirculating anodic antigen (CAA)diagnosislow endemic areaPOC-CCA testpolymerase chain reaction (PCR)Schistosoma mansoniup-converting phosphor lateral-flow assay

Identifiers

PMID31019510
PMCPMC6458306
OpenAlexW2933535066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.