Evidence map›Paper›PMID 31019449›Full record

ArticleFrontiers in neuroscience2019

Response of Mouse Visual Cortical Neurons to Electric Stimulation of the Retina.

Sang Baek Ryu, Paul Werginz, Shelley I Fried

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Implications of Neural Plasticity in Retinal Prosthesis.Investigative ophthalmology & visual science · 2022
    Article
  5. Offset Responses in the Auditory Cortex Show Unique History Dependence.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  6. Article
  7. Review
  8. Article
  9. Transcranial Focused Ultrasound for Noninvasive Neuromodulation of the Visual Cortex.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Sang Baek RyuBoston VA Healthcare System, Boston, MA, United States.
Paul WerginzDepartment of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Shelley I FriedBoston VA Healthcare System, Boston, MA, United States.
Harvard University · USVA Boston Healthcare System · US

Funding

Micro-coil implants for cortical activationU01NS099700 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI FRIED, SHELLEY · 2016 to 2018
$2.9M
Towards improved efficacy of retinal prostheticsI01RX001663 · VA · VA BOSTON HEALTH CARE SYSTEM · PI FRIED, SHELLEY · 2015 to 2017
–
Austrian Science Fund FWF J 3947NINDS NIH HHS U01 NS099700RRD VA I01 RX001663
6 · The paper itself

Abstract

Retinal prostheses strive to restore vision to the blind by electrically stimulating the neurons that survive the disease process. Clinical effectiveness has been limited however, and much ongoing effort is devoted toward the development of improved stimulation strategies, especially ones that better replicate physiological patterns of neural signaling. Here, to better understand the potential effectiveness of different stimulation strategies, we explore the responses of neurons in the primary visual cortex to electric stimulation of the retina. A 16-channel implantable microprobe was used to record single unit activities

Indexed as

electrical stimulationextraocular stimulationprimary visual cortexretinasingle unit activity

Identifiers

PMID31019449
PMCPMC6459047
OpenAlexW2926027906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.