Evidence map›Paper›PMID 31019442›Full record

ArticleBreast care (Basel, Switzerland)2019

Diagnostic Accuracy of Breast Medical Tactile Examiners (MTEs): A Prospective Pilot Study.

Michael P Lux, Julius Emons, Mayada R Bani, Marius Wunderle, Charlotte Sell, Caroline Preuss, Claudia Rauh, Sebastian M Jud, Felix Heindl, Hanna Langemann and 8 more

Abstract read
In one paragraph

Article in Breast care (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Michael P LuxDepartment of Gynecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen - EMN, Friedrich Alexander University of Erlangen-Nuremberg, Erlangen.
Julius EmonsDepartment of Gynecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen - EMN, Friedrich Alexander University of Erlangen-Nuremberg, Erlangen.
Mayada R BaniDepartment of Gynecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen - EMN, Friedrich Alexander University of Erlangen-Nuremberg, Erlangen.
Marius WunderleDepartment of Gynecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen - EMN, Friedrich Alexander University of Erlangen-Nuremberg, Erlangen.
Charlotte SellDepartment of Gynecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen - EMN, Friedrich Alexander University of Erlangen-Nuremberg, Erlangen.
Caroline PreussDepartment of Gynecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen - EMN, Friedrich Alexander University of Erlangen-Nuremberg, Erlangen.
Claudia RauhDepartment of Gynecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen - EMN, Friedrich Alexander University of Erlangen-Nuremberg, Erlangen.
Sebastian M JudDepartment of Gynecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen - EMN, Friedrich Alexander University of Erlangen-Nuremberg, Erlangen.
Felix HeindlDepartment of Gynecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen - EMN, Friedrich Alexander University of Erlangen-Nuremberg, Erlangen.
Hanna LangemannDepartment of Gynecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen - EMN, Friedrich Alexander University of Erlangen-Nuremberg, Erlangen.
Thomas GeyerDepartment of Gynecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen - EMN, Friedrich Alexander University of Erlangen-Nuremberg, Erlangen.
Anna-Lisa BrandlDepartment of Gynecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen - EMN, Friedrich Alexander University of Erlangen-Nuremberg, Erlangen.
Carolin C HackDepartment of Gynecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen - EMN, Friedrich Alexander University of Erlangen-Nuremberg, Erlangen.
Werner AdlerInstitute of Biometry and Epidemiology, Friedrich Alexander University of Erlangen-Nuremberg, Erlangen.
Rüdiger Schulz-WendtlandInstitute of Diagnostic Radiology, Erlangen University Hospital, Erlangen, Germany.
Matthias W BeckmannDepartment of Gynecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen - EMN, Friedrich Alexander University of Erlangen-Nuremberg, Erlangen.
Peter A FaschingDepartment of Gynecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen - EMN, Friedrich Alexander University of Erlangen-Nuremberg, Erlangen.
Paul GassDepartment of Gynecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen - EMN, Friedrich Alexander University of Erlangen-Nuremberg, Erlangen.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe usefulness of clinical breast examination (CBE) in general and in breast cancer screening programs has been a matter of debate. This study investigated whether adding vision-impaired medical tactile examiners (MTEs) improves the predictiveness of CBE for suspicious lesions and analyzed the feasibility and acceptability of this approach.

methodsThe prospective study included 104 patients. Physicians and MTEs performed CBEs, and mammography and ultrasound results were used as the gold standard. Sensitivity and specificity were calculated and logistic regression models were used to compare the predictive value of CBE by physicians alone, MTEs alone, and physicians and MTEs combined.

resultsFor CBEs by physicians alone, MTEs alone, and both combined, sensitivity was 71, 82, and 89% and specificity was 55, 45, and 35%, respectively. Using adjusted logistic regression models, the validated areas under the curve were 0.685, 0.692, and 0.710 (median bootstrapped p value (DeLong) = 0.381).

conclusionThe predictive value for a suspicious breast lesion in CBEs performed by MTEs in patients without prior surgery was similar to that of physician-conducted CBEs. Including MTEs in the CBE procedure in breast units thus appears feasible and could be a way of utilizing their skills.

Indexed as

Breast cancerClinical breast examinationEarly cancer detectionMedical tactile examinersScreening

Identifiers

PMID31019442
PMCPMC6465747

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.