ArticleInfectious diseases in obstetrics and gynecology2019
Human Papillomavirus (HPV) Infection in Early Pregnancy: Prevalence and Implications.
Article in Infectious diseases in obstetrics and gynecology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Association between human papillomavirus and preterm delivery: A systematic review and meta-analysis.Acta obstetricia et gynecologica Scandinavica · 2024Pooled it
- Association Between Maternal Human Papillomavirus Infection and Adverse Pregnancy Outcomes: Systematic Review and Meta-Analysis.The Journal of infectious diseases · 2020Pooled it
- Human papillomavirus infections during pregnancy and adverse pregnancy outcomes: a Scandinavian prospective mother-child cohort study.BMC pregnancy and childbirth · 2024Trial
- Risk of recurrent spontaneous preterm birth among those with persistent cervical HPV infection.Research square · 2026Article
- Prevalence of vaginal microecological disorder and its association with HPV infections in pregnant women attending prenatal examinations.Microbiology spectrum · 2026Article
- Approaches to Intraepithelial Cervical Neoplasia Management in Pregnancy: A Narrative Review.Life (Basel, Switzerland) · 2026Review
- The Effect of Human Papillomavirus Infection on Pregnancy Outcomes: A Scoping Review.Diagnostics (Basel, Switzerland) · 2026Review
- Human Papillomavirus in Reproductive Health and Pregnancy: Clinical Implications, Outcomes, and a Comprehensive Review of Vaccination.Vaccines · 2026Review
- HPV in Pregnancy: Implications for Screening, Vaccination, and Maternal-Fetal Health.Journal of pregnancy · 2026Review
- Epidemiological characteristics and risk factors of high-risk HPV infection, cervical cancer, and precancerous lesions among women in Southwestern China.Frontiers in oncology · 2025Article
- Effect of a Second Pregnancy on the HPV Serology in Mothers Followed Up in the Finnish Family HPV Study.Viruses · 2023Article
- Review
- Human Papillomavirus Transmission and Persistence in Pregnant Women and Neonates.JAMA pediatrics · 2023Article
- Maternal human papillomavirus infection during pregnancy and preterm delivery: A mother-child cohort study in Norway and Sweden.Acta obstetricia et gynecologica Scandinavica · 2023Article
- Evaluation of the impacts of photodynamic therapy on the prognosis of patients with hrHPV infection based on BTNL8 expression.Frontiers in oncology · 2023Article
- Prevalence, Diversity, and Risk Factors for Cervical HPV Infection in Women Screened for Cervical Cancer in Belém, Pará, Northern Brazil.Pathogens (Basel, Switzerland) · 2022Article
- Maternal HPV Infection and the Estimated Risks for Adverse Pregnancy Outcomes-A Systematic Review.Diagnostics (Basel, Switzerland) · 2022Review
- Obstetric complications in mothers with ADHD.Frontiers in reproductive health · 2022Article
- Prevalence of oncogenic human papillomavirus in pregnant adolescents, association with colpocytological changes, risk factors and obstetric outcomes.Clinics (Sao Paulo, Brazil) · 2022Article
- Maternal HPV Infection: Effects on Pregnancy Outcome.Viruses · 2021Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Young women (20-35 years) are at high risk of HPV infection, although the majority of the infections are asymptomatic and are cleared spontaneously by the host immune system. These are also the group of women who are sexually active and are in the population of pregnant women. During pregnancy, the changes in the hormonal milieu and immune response may favor persistence of HPV infection and may aid in transgenerational transmission thereby furthering the cancer risk. In the present study, we determined the prevalence of vaginal HPV infection in early pregnancy and attempted to relate with pregnancy outcome. Material and Methods: Vaginal cytology samples were collected from the condoms used to cover the vaginal sonography probe during a routine first trimester visit to the hospital. All women were followed up throughout pregnancy and childbirth. Maternal and neonatal outcomes were recorded. Results: We found a prevalence of HPV infection around 39.4% in our population. Interestingly all HPV positive women were infected with one or more high risk HPV viruses with an overlap of intermediate and low risk in 43% and 7.3%, respectively. Women with preterm prelabor rupture of membranes (PPROM) showed a statistically higher incidence in HPV positive (7.3%) group as compared to the HPV negative (3.2%) group. Conclusion: The prevalence of genital HPV infection is high during pregnancy (around 40%) and was associated with higher incidence of PPROM.
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