ArticleThe ISME journal2019
Intracellular Burkholderia Symbionts induce extracellular secondary infections; driving diverse host outcomes that vary by genotype and environment.
Article in The ISME journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 31 citations in OpenAlex.
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- Endophytic Bacterial Community, Core Taxa, and Functional Variations Within the Fruiting Bodies ofMicroorganisms · 2024Article
- Complex third-party effects in theProceedings. Biological sciences · 2024Article
- Article
- Predation-resistant Pseudomonas bacteria engage in symbiont-like behavior with the social amoeba Dictyostelium discoideum.The ISME journal · 2023Article
- Nutrient supplementation by genome-eroded Burkholderia symbionts of scale insects.The ISME journal · 2023Article
- Symbiotic bacteria, immune-like sentinel cells, and the response to pathogens in a social amoeba.Royal Society open science · 2023Article
- Article
- Complexities of Inferring Symbiont Function:Applied and environmental microbiology · 2022Article
- Context dependence in the symbiosis betweenEvolution letters · 2022Article
- Exploring bycatch diversity of organisms in whole genome sequencing of Erebidae moths (Lepidoptera).Scientific reports · 2021Article
- Novel Chlamydiae and Amoebophilus endosymbionts are prevalent in wild isolates of the model social amoeba Dictyostelium discoideum.Environmental microbiology reports · 2021Article
- Article
- An Evolutionary Arms Race BetweenFrontiers in microbiology · 2020Review
- Fitness costs and benefits vary for two facultativeEcology and evolution · 2019Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Symbiotic associations impact and are impacted by their surrounding ecosystem. The association between Burkholderia bacteria and the soil amoeba Dictyostelium discoideum is a tractable model to unravel the biology underlying symbiont-endowed phenotypes and their impacts. Several Burkholderia species stably associate with D. discoideum and typically reduce host fitness in food-rich environments while increasing fitness in food-scarce environments. Burkholderia symbionts are themselves inedible to their hosts but induce co-infections with secondary bacteria that can serve as a food source. Thus, Burkholderia hosts are "farmers" that carry food bacteria to new environments, providing a benefit when food is scarce. We examined the ability of specific Burkholderia genotypes to induce secondary co-infections and assessed host fitness under a range of co-infection conditions and environmental contexts. Although all Burkholderia symbionts intracellularly infected Dictyostelium, we found that co-infections are predominantly extracellular, suggesting that farming benefits are derived from extracellular infection of host structures. Furthermore, levels of secondary infection are linked to conditional host fitness; B. agricolaris infected hosts have the highest level of co-infection and have the highest fitness in food-scarce environments. This study illuminates the phenomenon of co-infection induction across Dictyostelium associated Burkholderia species and exemplifies the contextual complexity of these associations.
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