Evidence map›Paper›PMID 31019261›Full record

ArticleScientific reports2019

Bicontinuous Interfacially Jammed Emulsion Gels (bijels) as Media for Enabling Enzymatic Reactive Separation of a Highly Water Insoluble Substrate.

Sanghak Cha, Hyun Gyu Lim, Martin F Haase, Kathleen J Stebe, Gyoo Yeol Jung, Daeyeon Lee

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Nanomaterial Integration at Liquid-Liquid Interfaces for Green Catalysis.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Controlling Surfactant Adsorption on Highly Charged Nanoparticles to Stabilize Bijels.The journal of physical chemistry. C, Nanomaterials and interfaces · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Sanghak ChaDepartment of Chemical Engineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, Korea.
Hyun Gyu LimDepartment of Chemical Engineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, Korea.
Martin F HaaseDepartment of Chemical Engineering, Rowan University, Henry M. Rowan College of Engineering, Glassboro, NJ, 08028, USA.
Kathleen J StebeDepartment of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, PA, 19104, USA.ORCID http://orcid.org/0000-0003-0510-0513
Gyoo Yeol JungDepartment of Chemical Engineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, Korea. gyjung@postech.ac.kr.ORCID http://orcid.org/0000-0002-9742-3207
Daeyeon LeeDepartment of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, PA, 19104, USA. daeyeon@seas.upenn.edu.ORCID http://orcid.org/0000-0001-6679-290X
Pohang University of Science and Technology · KRUniversity of Pennsylvania · USRowan University · US

Funding

Time-efficient accurate 3D myocardium scar quantification using RAPID imagingR21EB017514 · NIBIB · UNIVERSITY OF WASHINGTON · PI YUAN, CHUN · 2014 to 2015
$445k
6 · The paper itself

Abstract

Although enzymes are efficient catalysts capable of converting various substrates into desired products with high specificity under mild conditions, their effectiveness as catalysts is substantially reduced when substrates are poorly water-soluble. In this study, to expedite the enzymatic conversion of a hydrophobic substrate, we use a bicontinuous interfacially jammed emulsion gel (bijel) which provides large interfacial area between two immiscible liquids: oil and water. Using lipase-catalyzed hydrolysis of tributyrin as a model reaction in a batch mode, we show that bijels can be used as media to enable enzymatic reaction. The bijel system gives a four-fold increase in the initial reaction rate in comparison to a stirred biphasic medium. Our results demonstrate that bijels are powerful biphasic reaction media to accelerate enzymatic reactions with various hydrophobic reagents. This work also demonstrates that bijels can potentially be used as reaction media to enable continuous reactive separations.

Indexed as

Butyric AcidCatalysisChromatography, High Pressure LiquidColloidsEmulsionsGelsGlycerolHydrolysisHydrophobic and Hydrophilic InteractionsLipaseMicroscopy, ConfocalModels, ChemicalMolecular StructureTriglyceridesWaterButyric AcidColloidsEmulsionsGelsGlycerolLipasetributyrinTriglyceridesWater

Identifiers

PMID31019261
PMCPMC6482178
OpenAlexW2940943039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.