ArticleProceedings of the National Academy of Sciences of the United States of America2019
Helical nanofiber yarn enabling highly stretchable engineered microtissue.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Fabrication of PCL Blended Highly Aligned Nanofiber Yarn from Dual-Nozzle Electrospinning System and Evaluation of the Influence on Introducing Collagen and Tropoelastin.ACS biomaterials science & engineering · 2025Article
- Shape Memory Collagen Scaffolds Sustain Large-Scale Cyclic Loading.ACS materials letters · 2025Article
- Spatially defined microenvironment for engineering organoids.Biophysics reviews · 2024Review
- Transcriptomics of tissue exosomes to investigate miR-195-5p's amelioration of endometrial fibrosis via the YAP-Smad7 pathway: an animal study.Journal of translational medicine · 2024Article
- Dual-Responsive MXene-Functionalized Wool Yarn Artificial Muscles.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- High-throughput and proteome-wide discovery of endogenous biomolecular condensates.Nature chemistry · 2024Article
- Designing an Effective and Scalable UV-Protective Cooling Textile with Nanoporous Fibers.Nano letters · 2023Article
- Biodegradable Polymer Electrospinning for Tendon Repairment.Polymers · 2023Review
- Bioresource Upgrade for Sustainable Energy, Environment, and Biomedicine.Nano-micro letters · 2023Review
- How Advancing is Peripheral Nerve Regeneration Using Nanofiber Scaffolds? A Comprehensive Review of the Literature.International journal of nanomedicine · 2023Review
- Shape-Programmable Liquid Metal Fibers.Biosensors · 2022Article
- Reciprocity of Cell Mechanics with Extracellular Stimuli: Emerging Opportunities for Translational Medicine.Small (Weinheim an der Bergstrasse, Germany) · 2022Review
- State-of-the-art review of advanced electrospun nanofiber yarn-based textiles for biomedical applications.Applied materials today · 2022Review
- Arrowhead Composite Microneedle Patches with Anisotropic Surface Adhesion for Preventing Intrauterine Adhesions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Emerging polymeric electrospun fibers: From structural diversity to application in flexible bioelectronics and tissue engineering.Exploration (Beijing, China) · 2022Article
- Advanced Nanofiber-Based Scaffolds for Achilles Tendon Regenerative Engineering.Frontiers in bioengineering and biotechnology · 2022Review
- Volumetric compression develops noise-driven single-cell heterogeneity.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Chinese herb microneedle patch for wound healing.Bioactive materials · 2021Article
- Versatile Ice Microneedles for Transdermal Delivery of Diverse Actives.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Article
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Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Development of microtissues that possess mechanical properties mimicking those of native stretchable tissues, such as muscle and tendon, is in high demand for tissue engineering and regenerative medicine. However, regardless of the significant advances in synthetic biomaterials, it remains challenging to fabricate living microtissue with high stretchability because application of large strains to microtissues can damage the cells by rupturing their structures. Inspired by the hierarchical helical structure of native fibrous tissues and its behavior of nonaffine deformation, we develop a highly stretchable and tough microtissue fiber made up of a hierarchical helix yarn scaffold, scaling from nanometers to millimeters, that can overcome this limitation. This microtissue can be stretched up to 15 times its initial length and has a toughness of 57 GJ m
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.