Evidence map›Paper›PMID 31019070›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Frequency of DNA end joining

Sham Sunder, Thomas E Wilson

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. The mechanisms of human lymphoid chromosomal translocations and their medical relevance.Critical reviews in biochemistry and molecular biology · 2022
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. The Cyclically SeasonalFrontiers in genetics · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sham SunderDepartment of Pathology, University of Michigan, Ann Arbor, MI 48109.
Thomas E WilsonDepartment of Pathology, University of Michigan, Ann Arbor, MI 48109; wilsonte@umich.edu.ORCID 0000-0002-8345-4985
University of Michigan · US

Funding

Systematic Genetic Analysis of Yeast NHEJR01GM120767 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WILSON, THOMAS EDWARD · 2016 to 2025
$2.8M
NIGMS NIH HHS R01 GM120767
6 · The paper itself

Abstract

DNA double-strand breaks (DSBs) are serious genomic insults that can lead to chromosomal rearrangements if repaired incorrectly. To gain insight into the nuclear mechanisms contributing to these rearrangements, we developed an assay in yeast to measure

Indexed as

DNA Breaks, Double-StrandedSaccharomyces cerevisiae3-Isopropylmalate DehydrogenaseDNA End-Joining RepairGene Expression Regulation, FungalGenetic LociGenome, FungalSaccharomyces cerevisiae Proteins3-Isopropylmalate DehydrogenaseLEU2 protein, S cerevisiaeSaccharomyces cerevisiae Proteinsgenome rearrangementhomologous recombinationnonhomologous end joiningsingle-strand annealingtranslocation

Identifiers

PMID31019070
PMCPMC6510992
OpenAlexW2940513658

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.