Evidence map›Paper›PMID 31018618›Full record

ArticleMolecules (Basel, Switzerland)2019

Microwave-Assisted Synthesis of Trazodone and Its Derivatives as New 5-HT

Jolanta Jaśkowska, Przemysław Zaręba, Paweł Śliwa, Edyta Pindelska, Grzegorz Satała, Zbigniew Majka

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. New Pharmaceutical Salts of Trazodone.Molecules (Basel, Switzerland) · 2021
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jolanta JaśkowskaInstitute of Organic Chemistry and Technology, Faculty of Chemical and Engineering and Technology, Cracow University of Technology, 24 Warszawska Street, 31-155 Cracow, Poland. jaskowskaj@chemia.pk.edu.pl.ORCID 0000-0001-6855-3531
Przemysław ZarębaInstitute of Organic Chemistry and Technology, Faculty of Chemical and Engineering and Technology, Cracow University of Technology, 24 Warszawska Street, 31-155 Cracow, Poland. pzareba@chemia.pk.edu.pl.
Paweł ŚliwaInstitute of Organic Chemistry and Technology, Faculty of Chemical and Engineering and Technology, Cracow University of Technology, 24 Warszawska Street, 31-155 Cracow, Poland. psliwa@chemia.pk.edu.pl.ORCID 0000-0001-9662-8481
Edyta PindelskaDepartment of Analytical Chemistry and Biomaterials, Faculty of Pharmacy with the Laboratory Medicine Division, Medical University of Warsaw, Banacha 1, 02-093 Warsaw, Poland. edyta.pindelska@wum.edu.pl.
Grzegorz SatałaDepartment of Medicinal Chemistry, Institute of Pharmacology-Polish Academy of Sciences, 12 Smętna Street, 31-343 Cracow, Poland. satala@if-pan.krakow.pl.
Zbigniew MajkaTM Labs Sp. z o.o., Al. W. Beliny-Prażmowskiego 14, 31-514 Kraków, Poland. zbigniew.majka@tmlabs.pl.
Cracow University of Technology · PLMaj Institute of Pharmacology · PLMedical University of Warsaw · PL

Funding

Narodowe Centrum Badań i Rozwoju LIDER/015/L-6/14/NCBR/2015
6 · The paper itself

Abstract

Trazodone, a well-known antidepressant drug widely used throughout the world, works as a 5-hydroxytryptamine (5-HT

Indexed as

Chemistry Techniques, SyntheticAdrenergic AntagonistsAnimalsAntidepressive AgentsBinding SitesCarbonatesCrystallography, X-RayHumansLigandsMicrowavesMolecular Docking SimulationPotassiumProtein BindingProtein Conformation, alpha-HelicalProtein Conformation, beta-StrandProtein Interaction Domains and MotifsAdrenergic AntagonistsAntidepressive AgentsCarbonatesLigandsPotassiumpotassium carbonateReceptor, Serotonin, 5-HT1AReceptor, Serotonin, 5-HT2ASelective Serotonin Reuptake InhibitorsTrazodone5-HT1A ligandslong-chain arylpiperazinesmicrowave (MW)-assisted synthesisserotonin receptor ligandstrazodone derivativestrazodone synthesis

Identifiers

PMID31018618
PMCPMC6515286
OpenAlexW2942171429

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.