Evidence map›Paper›PMID 31018602›Full record

ReviewCells2019

Cross-Kingdom Small RNAs Among Animals, Plants and Microbes.

Jun Zeng, Vijai Kumar Gupta, Yueming Jiang, Bao Yang, Liang Gong, Hong Zhu

Abstract readReview
In one paragraph

Review in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Isolation of Fusobacterium nucleatum-Induced Host Exosomal sRNAs.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  6. Review
  7. Review
  8. A Potential Regulatory Network of Selected Human Erythrocytic miRNAs withMicroRNA (Shariqah, United Arab Emirates) · 2025
    Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Metallo-antiviral aspirants:European journal of medicinal chemistry reports · 2023
    Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Frontiers in immunology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jun ZengKey Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China. junzeng@scbg.ac.cn.
Vijai Kumar GuptaDepartment of Chemistry and Biotechnology, School of Science, Tallinn University of Technology, 12618 Tallinn, Estonia. vijaifzd@gmail.com.
Yueming JiangKey Laboratory of Plant Resource Conservation and Sustainable Utilization, Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China. ymjiang@scbg.ac.cn.
Bao YangKey Laboratory of Plant Resource Conservation and Sustainable Utilization, Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China. yangbao@scbg.ac.cn.
Liang GongKey Laboratory of Plant Resource Conservation and Sustainable Utilization, Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China. lianggong@scbg.ac.cn.
Hong ZhuKey Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China. zhuhong@scbg.ac.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Small RNAs (sRNAs), a class of regulatory non-coding RNAs around 20~30-nt long, including small interfering RNAs (siRNAs) and microRNAs (miRNAs), are critical regulators of gene expression. Recently, accumulating evidence indicates that sRNAs can be transferred not only within cells and tissues of individual organisms, but also across different eukaryotic species, serving as a bond connecting the animal, plant, and microbial worlds. In this review, we summarize the results from recent studies on cross-kingdom sRNA communication. We not only review the horizontal transfer of sRNAs among animals, plants and microbes, but also discuss the mechanism of RNA interference (RNAi) signal transmission via cross-kingdom sRNAs. We also compare the advantages of host-induced gene silencing (HIGS) and spray-induced gene silencing (SIGS) technology and look forward to their applicable prospects in controlling fungal diseases.

Indexed as

AnimalsBacteriaGene Expression RegulationGene SilencingGene Transfer, HorizontalHumansMicroRNAsPlantsRNA, BacterialRNA, PlantRNA, Small InterferingRNA, Small UntranslatedMicroRNAsRNA, BacterialRNA, PlantRNA, Small InterferingRNA, Small Untranslatedcrop protectioncross-kingdom RNAiHIGSRNA interferenceSIGSsmall RNAs

Identifiers

PMID31018602
PMCPMC6523504

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.