Evidence map›Paper›PMID 31018588›Full record

ReviewViruses2019

A Bioinformatics View of Glycan⁻Virus Interactions.

Philippe Le Mercier, Julien Mariethoz, Josefina Lascano-Maillard, François Bonnardel, Anne Imberty, Sylvie Ricard-Blum, Frédérique Lisacek

Abstract readReview
In one paragraph

Review in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Role of Extracellular Vesicles in Liver Diseases.Life (Basel, Switzerland) · 2023
    Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Philippe Le MercierSwiss-Prot Group, SIB Swiss Institute of Bioinformatics, 1211 Geneva, Switzerland. philippe.lemercier@sib.swiss.
Julien MariethozProteome Informatics Group, SIB Swiss Institute of Bioinformatics, 1211 Geneva, Switzerland. julien.mariethoz@sib.swiss.
Josefina Lascano-MaillardProteome Informatics Group, SIB Swiss Institute of Bioinformatics, 1211 Geneva, Switzerland. Josefina.LascanoMaillard@unige.ch.
François BonnardelProteome Informatics Group, SIB Swiss Institute of Bioinformatics, 1211 Geneva, Switzerland. francois.bonnardel@cermav.cnrs.fr.
Anne ImbertyUniversité Grenoble Alpes, CNRS, CERMAV, 38041 Grenoble, France. anne.imberty@cermav.cnrs.fr.
Sylvie Ricard-BlumInstitut de Chimie et Biochimie Moléculaires et Supramoléculaires, UMR 5246 CNRS - Université Lyon 1, 69622 Villeurbanne Cedex, France. sylvie.ricard-blum@univ-lyon1.fr.
Frédérique LisacekProteome Informatics Group, SIB Swiss Institute of Bioinformatics, 1211 Geneva, Switzerland. frederique.lisacek@sib.swiss.

Funding

UniProt: A centralized protein sequence and function resourceU41HG007822 · NHGRI · EUROPEAN MOLECULAR BIOLOGY LABORATORY · PI BATEMAN, ALEX · 2014 to 2017
$21.9M
NIGMS NIH HHS U41HG007822
6 · The paper itself

Abstract

Evidence of the mediation of glycan molecules in the interaction between viruses and their hosts is accumulating and is now partially reflected in several online databases. Bioinformatics provides convenient and efficient means of searching, visualizing, comparing, and sometimes predicting, interactions in numerous and diverse molecular biology applications related to the -omics fields. As viromics is gaining momentum, bioinformatics support is increasingly needed. We propose a survey of the current resources for searching, visualizing, comparing, and possibly predicting host-virus interactions that integrate the presence and role of glycans. To the best of our knowledge, we have mapped the specialized and general-purpose databases with the appropriate focus. With an illustration of their potential usage, we also discuss the strong and weak points of the current bioinformatics landscape in the context of understanding viral infection and the immune response to it.

Indexed as

Computational BiologyHost Microbial InteractionsVirusesDatabases, FactualHumansPolysaccharidesReceptors, VirusViral ProteinsVirus DiseasesPolysaccharidesReceptors, VirusViral Proteinsbioinformaticscarbohydratedatabasedata integrationglycanhost–virus interactionsimmunologyinteroperability

Identifiers

PMID31018588
PMCPMC6521074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.