Evidence map›Paper›PMID 31018549›Full record

ReviewMolecules (Basel, Switzerland)2019

Red Beetroot and Betalains as Cancer Chemopreventative Agents.

John F Lechner, Gary D Stoner

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 104 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Investigation of beetroot (Frontiers in oncology · 2026
    Article
  5. Effects of the Polar Fraction ofInternational journal of molecular sciences · 2025
    Article
  6. Article
  7. Beetroot (Narra J · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. The therapeutic potential of red beetroot (Food science & nutrition · 2024
    Article
  13. Review
  14. Pharmaceuticals (Basel, Switzerland) · 2024
    Article
  15. Article
  16. Review
  17. Article
  18. Green Cancer Prevention and Beyond.Cancer prevention research (Philadelphia, Pa.) · 2024
    Review
  19. Review
  20. Dietary Beetroot Juice - Effects in Patients with COPD: A Review.International journal of chronic obstructive pulmonary disease · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

John F LechnerDepartment of Microbiology and Immunology, Montana State University, Bozeman, MT 59717, USA. johnf.lechner@gmail.com.
Gary D StonerDepartment of Microbiology and Immunology, Montana State University, Bozeman, MT 59717, USA. gstoner@montana.edu.
Montana State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carcinogenesis is the process whereby a normal cell is transformed into a neoplastic cell. This action involves several steps starting with initiation and followed by promotion and progression. Driving these stages are oxidative stress and inflammation, which in turn encompasses a myriad of aberrant gene expressions, both within the transforming cell population and the cells within the surrounding lesion. Chemoprevention of cancer with bioreactive foods or their extracted/purified components occurs via normalizing these inappropriate gene activities. Various foods/agents have been shown to affect different gene expressions. In this review, we discuss whereby the chemoprevention activities of the red beetroot itself may disrupt carcinogenesis and the activities of the water-soluble betalains extracted from the plant.

Indexed as

AnimalsAnticarcinogenic AgentsAntioxidantsBetalainsBeta vulgarisCarcinogenesisCell Line, TumorFlavonolsGene Expression Regulation, NeoplasticHumansMiceNeoplasm ProteinsNeoplasmsPhenolsPlant ExtractsPlant RootsAnticarcinogenic AgentsAntioxidantsBetalainsFlavonolsNeoplasm ProteinsPhenolsPlant ExtractsTriterpenesanti-oxidantapoptosisbeetrootbetaninscancer chemopreventioninflammation

Identifiers

PMID31018549
PMCPMC6515411
OpenAlexW2938348196

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.