Evidence map›Paper›PMID 31018496›Full record

ArticleViruses2019

A Functional Ubiquitin-Proteasome System is Required for Efficient Replication of New World Mayaro and Una Alphaviruses.

Yessica Y Llamas-González, Dalkiria Campos, Juan M Pascale, Juan Arbiza, José González-Santamaría

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

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  5. Mayaro virus pathogenesis and immunity in rhesus macaques.PLoS neglected tropical diseases · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Yessica Y Llamas-GonzálezGrupo de Biología Celular y Molecular de Arbovirus, Instituto Conmemorativo Gorgas de Estudios de la Salud, Panamá 0816-02593, Panama. qfb.y.llamas@gmail.com.ORCID 0000-0003-3404-1313
Dalkiria CamposGrupo de Biología Celular y Molecular de Arbovirus, Instituto Conmemorativo Gorgas de Estudios de la Salud, Panamá 0816-02593, Panama. dcampos@gorgas.gob.pa.
Juan M PascaleDirección de Investigación y Desarrollo Tecnológico, Instituto Conmemorativo Gorgas de Estudios de la Salud, Panamá 0816-02593, Panama. jmpascale@gorgas.gob.pa.
Juan ArbizaSeccción de Virología, Facultad de Ciencias, Universidad de la República, Montevideo 11400, Uruguay. jarbiza@fcien.edu.uy.
José González-SantamaríaGrupo de Biología Celular y Molecular de Arbovirus, Instituto Conmemorativo Gorgas de Estudios de la Salud, Panamá 0816-02593, Panama. jgonzalezsantamaria@gorgas.gob.pa.ORCID 0000-0003-1244-3477
Instituto Conmemorativo Gorgas de Estudios de la Salud · PAUniversidad de la República de Uruguay · UYUniversidad de Panamá · PA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mayaro (MAYV) and Una (UNAV) are emerging arboviruses belonging to the

Indexed as

Virus ReplicationAcetylcysteineAlphavirusAnimalsAntiviral AgentsChlorocebus aethiopsCysteine Proteinase InhibitorsCytoplasmHeLa CellsHumansLeupeptinsProteasome Endopeptidase ComplexProteasome InhibitorsVero CellsAcetylcysteineAntiviral Agentsbenzyloxycarbonylleucyl-leucyl-leucine aldehydeCysteine Proteinase InhibitorslactacystinLeupeptinsProteasome Endopeptidase ComplexProteasome InhibitorsalphavirusesinhibitionMayaroreplicationubiquitin-proteasome systemUnaviral proteins

Identifiers

PMID31018496
PMCPMC6520948
OpenAlexW2940184969

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.