Evidence map›Paper›PMID 31018241›Full record

ArticleInternational journal of cancer2019

Diabetes mellitus, genetic variants in the insulin-like growth factor pathway and colorectal cancer risk.

Sander de Kort, Colinda C J M Simons, Piet A van den Brandt, Maryska L G Janssen-Heijnen, Silvia Sanduleanu, Ad A M Masclee, Matty P Weijenberg

Open access · hybridAbstract read
In one paragraph

Article in International journal of cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Observational
  6. Article
  7. The odds of neoplasia in dogs with and without diabetes mellitus.Journal of veterinary internal medicine · 2022
    Article
  8. Review
  9. Article
  10. Prospective evaluation of dietary and lifestyle pattern indices with risk of colorectal cancer in a cohort of younger women.Annals of oncology : official journal of the European Society for Medical Oncology · 2021
    Article
  11. Article
  12. Article
  13. Night-Shift Work Duration and Risk of Colorectal Cancer According toCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sander de KortDepartment of Epidemiology, GROW-School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.ORCID 0000-0001-6956-0821
Colinda C J M SimonsDepartment of Epidemiology, GROW-School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.ORCID 0000-0002-0085-5186
Piet A van den BrandtDepartment of Epidemiology, GROW-School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.ORCID 0000-0001-8781-8099
Maryska L G Janssen-HeijnenDepartment of Epidemiology, GROW-School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.
Silvia SanduleanuDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.
Ad A M MascleeDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.
Matty P WeijenbergDepartment of Epidemiology, GROW-School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.
Maastricht University · NLMaastricht University Medical Centre · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic variation in the insulin-like growth factor (IGF) pathway may further increase the risk of colorectal cancer (CRC) associated with type 2 diabetes mellitus (T2DM). Joint effects of T2DM and genetic variation in the IGF pathway on CRC risk can increase mechanistic insights. Participants from the Netherlands Cohort Study (n = 120, 852) completed a baseline questionnaire in 1986 when 55-69 years old (case-cohort, n

Indexed as

Dinucleotide RepeatsSignal TransductionAgedAge of OnsetColorectal NeoplasmsDiabetes Mellitus, Type 2FemaleGenetic Predisposition to DiseaseHumansInsulin-Like Growth Factor IMaleMiddle AgedNetherlandsPrevalenceProportional Hazards ModelsProspective StudiesIGF1 protein, humanInsulin-Like Growth Factor Icohort studiescolorectal cancerdiabetes mellitusgene-environment interactionsinsulin-like growth factors

Identifiers

PMID31018241
PMCPMC6767781
OpenAlexW2941891154

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.