ArticlePLoS biology2019
An elucidation of over a century old enigma in genetics-Heterosis.
Article in PLoS biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed.
- Effects of Ploidy on Relationship Between Outbreeding Response and Fitness in a Plant Selfing Species.Ecology and evolution · 2025Article
- The mRNA-lncRNA landscape of multiple tissues uncovers key regulators and molecular pathways that underlie heterosis for feed intake and efficiency in laying chickens.Genetics, selection, evolution : GSE · 2023Article
- Epigenetic Regulation in Heterosis and Environmental Stress: The Challenge of Producing Hybrid Epigenomes to Face Climate Change.Epigenomes · 2023Review
- Heterosis patterns and sources of self-compatibility, cross-compatibility and key nut traits within single and double hybrid crosses of kola [Cola nitida (Vent) Schott and Endl.].Scientific reports · 2023Article
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- Evolution of dominance in gene expression pattern associated with phenotypic robustness.BMC ecology and evolution · 2021Article
- Improved redox homeostasis owing to the up-regulation of one-carbon metabolism and related pathways is crucial for yeast heterosis at high temperature.Genome research · 2021Article
- Heterosis and Hybrid Crop Breeding: A Multidisciplinary Review.Frontiers in genetics · 2021Review
- Integrated Analysis of mRNA and Non-coding RNA Transcriptome in Pepper (Frontiers in genetics · 2021Article
- Genome-wide analysis of epigenetic and transcriptional changes associated with heterosis in pigeonpea.Plant biotechnology journal · 2020Article
- Harnessing genomics to fast-track genetic improvement in aquaculture.Nature reviews. Genetics · 2020Review
- Proposal of a New Hybrid Breeding Method Based on Genotyping, Inter-Pollination, Phenotyping and Paternity Testing of Selected Elite FFrontiers in plant science · 2019Article
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Abstract
Recognition and exploitation of hybrid vigor or heterosis among individual crosses of plants and animals has a long and distinguished history. Its manifestation is influenced by a combination of genetic, epigenetic, phenotypic, and environmental factors. Although heterosis is known to be governed by both dominant and epistatic gene action, its expression is greatly influenced by nonlinear interaction among epigenetic and phenotypic (phenomic) components. The magnitude of heterosis is generally inferred post hoc by the phenotypic performance of hybrids among laboriously made individual crosses. The expression of dominance, however, is nonlinear at the cellular level and obeys the principles underlying metabolic flux. Then, is it possible to exploit these relationships to predict heterosis? Vasseur and colleagues have indeed demonstrated the feasibility of such an approach in a series of experiments taking integrated biochemical and computational approaches, as well as testing these results on large samples of model organisms. The results offer promise toward phenomic prediction of heterosis across a wide array of organisms.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.