Evidence map›Paper›PMID 31017745›Full record

ArticleCancer cytopathology2019

Extending expressed RNA genomics from surgical decision making for cytologically indeterminate thyroid nodules to targeting therapies for metastatic thyroid cancer.

Syed Z Ali, Allan Siperstein, Peter M Sadow, Allan C Golding, Giulia C Kennedy, Richard T Kloos, Paul W Ladenson

Abstract read
In one paragraph

Article in Cancer cytopathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Molecular Variants and Their Risks for Malignancy in Cytologically Indeterminate Thyroid Nodules.Thyroid : official journal of the American Thyroid Association · 2019
    Pooled it
  3. The Molecular Heterogeneity of NRAS Variants in Thyroid Nodules.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. A five-gene panel refines differential diagnosis of thyroid nodules.Journal of clinical laboratory analysis · 2021
    Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Syed Z AliDepartment of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland.
Allan SipersteinDepartment of Endocrine Surgery, Cleveland Clinic, Cleveland, Ohio.
Peter M SadowDepartment of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Allan C GoldingDepartment of Medicine, Florida International University, Memorial Healthcare System, Hollywood, Florida.
Giulia C KennedyDepartment of Clinical Affairs, Veracyte Inc, South San Francisco, California.
Richard T KloosDepartment of Medical Affairs, Veracyte Inc, South San Francisco, California.ORCID 0000-0003-4183-7387
Paul W LadensonDivision of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Funding

Strategies to Overcome Immune Resistance in Head and Neck CancersP01CA240239 · NCI · YALE UNIVERSITY · PI MEMPEL, THORSTEN ROMAN · 2019 to 2023
$8.4M
NCI NIH HHS P01 CA240239
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adenocarcinoma, FollicularBiomarkers, TumorBiopsy, Fine-NeedleClinical Decision-MakingDiagnosis, DifferentialFeasibility StudiesGene Expression Regulation, NeoplasticHumansMachine LearningPrecision MedicineReagent Kits, DiagnosticRNA, MessengerRNA, NeoplasmRNA-SeqThyroid Cancer, PapillaryThyroidectomyBiomarkers, TumorReagent Kits, DiagnosticRNA, MessengerRNA, Neoplasmclinical validationindeterminate cytologymachine learningmolecular diagnosticsthyroid nodule

Identifiers

PMID31017745
PMCPMC6618055

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.