Evidence map›Paper›PMID 31017712›Full record

ArticleChembiochem : a European journal of chemical biology2019

Biochemical and Structural Characterization of XoxG and XoxJ and Their Roles in Lanthanide-Dependent Methanol Dehydrogenase Activity.

Emily R Featherston, Hannah R Rose, Molly J McBride, Ellison M Taylor, Amie K Boal, Joseph A Cotruvo

Open access · greenAbstract read
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Article
  3. Functional organization and regulatory logic of theApplied and environmental microbiology · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Modulating metal-centered dimerization of a lanthanide chaperone protein for separation of light lanthanides.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Structure-driven development of a biomimetic rare earth artificial metalloprotein.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Understanding the chemistry of the artificial electron acceptors PES, PMS, DCPIP and Wurster's Blue in methanol dehydrogenase assays.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2020
    Article
  18. Lanthanide-Dependent Methylotrophs of the FamilyApplied and environmental microbiology · 2019
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Emily R FeatherstonDepartment of Chemistry, The Pennsylvania State University, University Park, PA, 16802, USA.ORCID 0000-0003-1338-6611
Hannah R RoseDepartment of Chemistry, The Pennsylvania State University, University Park, PA, 16802, USA.ORCID 0000-0002-7982-2001
Molly J McBrideDepartment of Chemistry, The Pennsylvania State University, University Park, PA, 16802, USA.ORCID 0000-0003-3832-1355
Ellison M TaylorDepartment of Chemistry, The Pennsylvania State University, University Park, PA, 16802, USA.
Amie K BoalDepartment of Chemistry, The Pennsylvania State University, University Park, PA, 16802, USA.ORCID 0000-0002-1234-8472
Joseph A CotruvoDepartment of Chemistry, The Pennsylvania State University, University Park, PA, 16802, USA.ORCID 0000-0003-4243-8257
Pennsylvania State University · US

Funding

Mapping the Structural Basis for Mechanistic Diversity in Metalloenzyme SuperfamiliesR35GM119707 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI Amie K Boal · 2016 to 2026
$5.0M
High-Speed High-Sensitivity Detector for X-ray Micro-Crystallography at GM/CA@APSS10OD012289 · OD · UNIVERSITY OF CHICAGO · PI FISCHETTI, ROBERT F. · 2014 to 2014
$2.0M
NIGMS NIH HHS GM119707NIGMS NIH HHS R35 GM119707NIH HHS S10 OD012289Pennsylvania State UniversityUS Department of Energy DE-AC02-05CH11231US Department of Energy DE-AC02-06CH11357
6 · The paper itself

Abstract

Lanthanide (Ln)-dependent methanol dehydrogenases (MDHs) have recently been shown to be widespread in methylotrophic bacteria. Along with the core MDH protein, XoxF, these systems contain two other proteins, XoxG (a c-type cytochrome) and XoxJ (a periplasmic binding protein of unknown function), about which little is known. In this work, we have biochemically and structurally characterized these proteins from the methyltroph Methylobacterium extorquens AM1. In contrast to results obtained in an artificial assay system, assays of XoxFs metallated with La

Indexed as

Alcohol OxidoreductasesBacterial ProteinsCytochrome c GroupEnzyme AssaysKineticsLanthanoid Series ElementsMethanolMethylobacterium extorquensOxidation-ReductionPeriplasmic Binding ProteinsRhodothermusSaccharomyces cerevisiaealcohol dehydrogenase (acceptor)Alcohol OxidoreductasesBacterial ProteinsCytochrome c GroupLanthanoid Series ElementsMethanolPeriplasmic Binding Proteinscytochrome clanthanidesmethanol dehydrogenaserare earthsreduction potential

Identifiers

PMID31017712
PMCPMC6814260
OpenAlexW2966416824

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.