Evidence map›Paper›PMID 31017307›Full record

ArticleBritish journal of pharmacology2020

Hydrogen sulfide inhibits calcification of heart valves; implications for calcific aortic valve disease.

Katalin Éva Sikura, László Potor, Tamás Szerafin, Melinda Oros, Péter Nagy, Gábor Méhes, Zoltán Hendrik, Abolfazl Zarjou, Anupam Agarwal, Niké Posta and 5 more

Open access · hybridAbstract read
In one paragraph

Article in British journal of pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. The Role of Hydrogen Sulfide in Plaque Stability.Antioxidants (Basel, Switzerland) · 2022
    Review
  8. CTH/HInternational journal of molecular sciences · 2022
    Article
  9. Article
  10. Vasoactive Effects of Chronic Treatment with Fructose and Slow-Releasing HInternational journal of molecular sciences · 2022
    Article
  11. The Gasotransmitter Hydrogen Sulfide (HAntioxidants (Basel, Switzerland) · 2021
    Article
  12. Review
  13. Review
  14. Hyperphosphatemia and Cardiovascular Disease.Frontiers in cell and developmental biology · 2021
    Review
  15. Review
  16. Article
  17. Article
  18. From primordial gas to the medicine cabinet.British journal of pharmacology · 2020
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 3 countries.

Katalin Éva SikuraHAS-UD Vascular Biology and Myocardial Pathophysiology Research Group, Hungarian Academy of Sciences, Debrecen, Hungary.
László PotorHAS-UD Vascular Biology and Myocardial Pathophysiology Research Group, Hungarian Academy of Sciences, Debrecen, Hungary.
Tamás SzerafinDepartment of Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Melinda OrosHAS-UD Vascular Biology and Myocardial Pathophysiology Research Group, Hungarian Academy of Sciences, Debrecen, Hungary.
Péter NagyDepartment of Molecular Immunology and Toxicology, National Institute of Oncology, Budapest, Hungary.ORCID 0000-0003-3393-235X
Gábor MéhesDepartment of Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Zoltán HendrikDepartment of Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Abolfazl ZarjouDepartment of Medicine, Division of Nephrology, Nephrology Research and Training Center and Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, Alabama.
Anupam AgarwalDepartment of Medicine, Division of Nephrology, Nephrology Research and Training Center and Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, Alabama.
Niké PostaDepartment of Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Roberta TorregrossaCollege of Medicine and Health, University of Exeter Medical School, Exeter, UK.
Matthew WhitemanCollege of Medicine and Health, University of Exeter Medical School, Exeter, UK.
Ibolya FürtösDepartment of Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
György BallaHAS-UD Vascular Biology and Myocardial Pathophysiology Research Group, Hungarian Academy of Sciences, Debrecen, Hungary.
József BallaHAS-UD Vascular Biology and Myocardial Pathophysiology Research Group, Hungarian Academy of Sciences, Debrecen, Hungary.ORCID 0000-0001-7923-2645
University of Debrecen · HUUniversity of Alabama at Birmingham · USUniversity of Exeter · GBNational Institute of Oncology · HU

Funding

Targeting Ferritin in Vascular Calcification Associated With CKDK08HL140294 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ZARJOU, ABOLFAZL · 2018 to 2022
$841k
Medical Research Council MC_PC_15047NHLBI NIH HHS K08 HL140294
6 · The paper itself

Abstract

background and purposeCalcification of heart valves is a frequent pathological finding in chronic kidney disease and in elderly patients. Hydrogen sulfide (H EXPERIMENTAL APPROACH: Effects of H KEY

resultsIn human VIC, H CONCLUSIONS AND IMPLICATIONS: The endogenous CSE-CBS/H LINKED ARTICLES: This article is part of a themed section on Hydrogen Sulfide in Biology & Medicine. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v177.4/issuetoc.

Indexed as

Aortic Valve DiseaseAortic Valve StenosisCalcinosisHydrogen SulfideAgedAnimalsAortic ValveCells, CulturedHumansMiceHydrogen Sulfide

Identifiers

PMID31017307
PMCPMC7024713
OpenAlexW2942097169

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.