Evidence map›Paper›PMID 31016966›Full record

ArticleACS infectious diseases2019

Small-Molecule Inhibitors of

Livia Shehaj, Santosh K Choudary, Kamlesh M Makwana, Mary C Gallo, Timothy F Murphy, Joshua A Kritzer

Open access · greenAbstract read
In one paragraph

Article in ACS infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Structure of theProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Frontiers in microbiology · 2022
    Article
  7. IgA: Structure, Function, and Developability.Antibodies (Basel, Switzerland) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Livia ShehajDepartment of Chemistry , Tufts University , 62 Talbot Avenue , Medford , Massachusetts 02155 , United States.
Santosh K ChoudaryDepartment of Chemistry , Tufts University , 62 Talbot Avenue , Medford , Massachusetts 02155 , United States.
Kamlesh M MakwanaDepartment of Chemistry , Tufts University , 62 Talbot Avenue , Medford , Massachusetts 02155 , United States.
Mary C GalloDepartment of Microbiology and Immunology , University at Buffalo, Jacobs School of Medicine and Biomedical Sciences , 3435 Main Street , Buffalo , New York 14203 , United States.
Timothy F MurphyDepartment of Microbiology and Immunology , University at Buffalo, Jacobs School of Medicine and Biomedical Sciences , 3435 Main Street , Buffalo , New York 14203 , United States.
Joshua A KritzerDepartment of Chemistry , Tufts University , 62 Talbot Avenue , Medford , Massachusetts 02155 , United States.ORCID 0000-0003-2878-6781
Tufts University · USUniversity at Buffalo, State University of New York · US

Funding

Persistent H. influenzae in COPD - virulence, vaccines and antibiotic resistanceR01AI019641 · NIAID · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 1985 to 2023
$7.9M
High-Throughput Assays for Inhibitors of Understudied Bacterial ProteasesR01GM111042 · NIGMS · TUFTS UNIVERSITY MEDFORD · PI KRITZER, JOSHUA A · 2015 to 2017
$856k
NIAID NIH HHS R01 AI019641NIGMS NIH HHS R01 GM111042
6 · The paper itself

Abstract

Newly identified, nontypable

Indexed as

Antiviral AgentsComputational BiologyDose-Response Relationship, DrugGenetic VariationHaemophilus influenzaeHigh-Throughput Screening AssaysSerine EndopeptidasesSerine Proteinase InhibitorsSmall Molecule LibrariesStructure-Activity RelationshipViral ProteinsVirulence FactorsAntiviral AgentsIgA-specific serine endopeptidaseSerine EndopeptidasesSerine Proteinase InhibitorsSmall Molecule LibrariesViral ProteinsVirulence Factorsantibacterial resistanceFRET assayhigh-throughput screeningIgA1 proteaseprotease inhibitors

Identifiers

PMID31016966
PMCPMC6625846
OpenAlexW2941808011

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.