Evidence map›Paper›PMID 31016943›Full record

ArticleSheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi2019

[Construction of controllable polyethylene glycol bioactive coating with hemocompatibility from the surface of modified glass substrate].

Yu Wei, Jingxun Zhang, Yuzhong Zhang, Xiantao Feng, Xuanhuang Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yu WeiSchool of Chemical and Pharmaceutical Engineering, Huanghuai University, Zhumadian, Henan 463000, P.R.China.wuxinren83@163.com.
Jingxun ZhangSchool of Chemical and Pharmaceutical Engineering, Huanghuai University, Zhumadian, Henan 463000, P.R.China.
Yuzhong ZhangHenan Jinkai Investment Holding Group, Kaifeng, Henan 475002, P.R.China.
Xiantao FengSchool of Chemical and Pharmaceutical Engineering, Huanghuai University, Zhumadian, Henan 463000, P.R.China.
Xuanhuang YangSchool of Chemical and Pharmaceutical Engineering, Huanghuai University, Zhumadian, Henan 463000, P.R.China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A diblock copolymer, poly(ethylene glycol) methacrylate-block-glycidyl methacrylate (PEGMA-GMA), was prepared on glass substrate by surface-initiated atom transfer radical polymerization (SI-ATRP), and endothelial specific peptide Arg-Glu-Asp-Val (REDV) was immobilized at the end of the PEGMA-GMA polymer brush by ring opening reaction through the rich epoxy groups in the GMA. The structure and hydrophilicity of the polymer brushes were characterized by static water contact angle, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM). The results showed that the REDV modified copolymer brushes were successfully constructed on the glass substrates. The REDV peptide immobilized onto surface was quantitatively characterized by ultraviolet-visible spectroscopy (UV-VIS). The blood compatibility of the coating was characterized by recalcification time and platelet adhesion assay. The results showed that the polymer coating had good blood compatibility. The multifunctional active polymer coating with PEGMA and peptide produced an excellent prospect in surface construction with endothelial cells selectivity.

Indexed as

Biocompatible MaterialsMethacrylatesPlatelet AdhesivenessPolyethylene GlycolsCells, CulturedEndothelial CellsGlassHumansImmobilized ProteinsOligopeptidesPolymersSurface Propertiesarginyl-glutamyl-aspartyl-valineBiocompatible MaterialsImmobilized ProteinsMethacrylatesOligopeptidesPolyethylene GlycolsPolymersactive polymer coatingglycidyl methacrylatepoly(ethylene glycol) methacrylatesurface-initiated atom transfer radical polymerization

Identifiers

PMID31016943
PMCPMC9929892

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.