ArticleDevelopmental science2019
The relationship between biological and psychosocial risk factors and resting-state functional connectivity in 2-month-old Bangladeshi infants: A feasibility and pilot study.
Article in Developmental science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Neural correlates of socioeconomic status in early childhood: a systematic review of the literature.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2021Pooled it
- A hierarchical model of early brain functional network development.Trends in cognitive sciences · 2025Review
- Infant EEG microstate dynamics relate to fine-grained patterns of infant attention during naturalistic play with caregivers.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Examining the relationship between psychosocial adversity and inhibitory control: A functional magnetic resonance imaging study of children growing up in extreme poverty.Journal of experimental child psychology · 2025Article
- Microstate Analysis of Continuous Infant EEG: Tutorial and Reliability.Brain topography · 2024Article
- A global multicohort study to map subcortical brain development and cognition in infancy and early childhood.Nature neuroscience · 2024Article
- Brain morphometry and chronic inflammation in Bangladeshi children growing up in extreme poverty.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Neural Network Functional Interactions Mediate or Suppress White Matter-Emotional Behavior Relationships in Infants.Biological psychiatry · 2023Article
- The Brain Imaging for Global Health (BRIGHT) Project: Longitudinal cohort study protocol.Gates open research · 2023Article
- Examining resting-state network connectivity in children exposed to perinatal maternal adversity using anatomically weighted functional connectivity (awFC) analyses; A preliminary report.Frontiers in neuroscience · 2023Article
- Examining the Role of Socioeconomic Status and Maternal Sensitivity in Predicting Functional Brain Network Connectivity in 5-Month-Old Infants.Frontiers in neuroscience · 2022Article
- Brain morphometry and diminished physical growth in Bangladeshi children growing up in extreme poverty: A longitudinal study.Developmental cognitive neuroscience · 2021Article
- Reliability of an automated gaze-controlled paradigm for capturing neural responses during visual and face processing in toddlerhood.Developmental psychobiology · 2021Article
- Prenatal stress dysregulates resting-state functional connectivity and sensory motifs.Neurobiology of stress · 2021Article
- Imaging the rapidly developing brain: Current challenges for MRI studies in the first five years of life.Developmental cognitive neuroscience · 2021Review
- Adversity in childhood is linked to mental and physical health throughout life.BMJ (Clinical research ed.) · 2020Article
- Using multiple short epochs optimises the stability of infant EEG connectivity parameters.Scientific reports · 2020Article
- Dyslexia as an adaptation to cortico-limbic stress system reactivity.Neurobiology of stress · 2020Review
- Relating anthropometric indicators to brain structure in 2-month-old Bangladeshi infants growing up in poverty: A pilot study.NeuroImage · 2020Article
- The relationship between biological and psychosocial risk factors and resting-state functional connectivity in 2-month-old Bangladeshi infants: A feasibility and pilot study.Developmental science · 2019Article
Corrections and comments
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Authors and funding
16 authors at 7 institutions in 2 countries.
Funding
Abstract
Childhood poverty has been associated with structural and functional alterations in the developing brain. However, poverty does not alter brain development directly, but acts through associated biological or psychosocial risk factors (e.g. malnutrition, family conflict). Yet few studies have investigated risk factors in the context of infant neurodevelopment, and none have done so in low-resource settings such as Bangladesh, where children are exposed to multiple, severe biological and psychosocial hazards. In this feasibility and pilot study, usable resting-state fMRI data were acquired in infants from extremely poor (n = 16) and (relatively) more affluent (n = 16) families in Dhaka, Bangladesh. Whole-brain intrinsic functional connectivity (iFC) was estimated using bilateral seeds in the amygdala, where iFC has shown susceptibility to early life stress, and in sensory areas, which have exhibited less susceptibility to early life hazards. Biological and psychosocial risk factors were examined for associations with iFC. Three resting-state networks were identified in within-group brain maps: medial temporal/striatal, visual, and auditory networks. Infants from extremely poor families compared with those from more affluent families exhibited greater (i.e. less negative) iFC in precuneus for amygdala seeds; however, no group differences in iFC were observed for sensory area seeds. Height-for-age, a proxy for malnutrition/infection, was not associated with amygdala/precuneus iFC, whereas prenatal family conflict was positively correlated. Findings suggest that it is feasible to conduct infant fMRI studies in low-resource settings. Challenges and practical steps for successful implementations are discussed.
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