ArticleClinical rheumatology2019
Nailfold capillary changes in adult new-onset dermatomyositis: a prospective cross-sectional study.
Article in Clinical rheumatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Nailfold microscopy in adult-onset dermatomyositis in association with myositis antibodies.Archives of dermatological research · 2024Pooled it
- Nailfold capillaroscopy in rheumatic connective tissue diseases.Reumatologia · 2026Review
- Dermatomyositis is characterized by JAK1-mediated monocyte-driven vasculopathy and inflammation.Science translational medicine · 2025Article
- Interstitial Lung Disease Secondary to Sjogren's Syndrome and Antisynthetase Syndrome: Converging Disease Trajectories.Medicina (Kaunas, Lithuania) · 2025Article
- Nailfold videocapillaroscopy in juvenile dermatomyositis: detailed correlations between microvascular abnormalities with clinical and laboratory parameters from an observational retrospective single-center study.Clinical rheumatology · 2025Observational
- Altered microvasculature in patients with adult-onset dermatomyositis using optical coherence tomography angiography.Scientific reports · 2025Article
- The usefulness of nailfold capillaroscopy in scleroderma-spectrum disorders: a single-centre observational study.Postepy dermatologii i alergologii · 2024Article
- Nailfold capillaroscopy findings of a multicentric multi-ethnic cohort of patients with idiopathic inflammatory myopathies.Clinical and experimental rheumatology · 2024Article
- Update on Cutaneous Signs to Assist in the Diagnosis of Dermatomyositis.Current rheumatology reports · 2022Review
- Nailfold capillary patterns correlate with age, gender, lifestyle habits, and fingertip temperature.PloS one · 2022Article
- Trichoscopic Signs in Dermatomyositis, Systemic Lupus Erythematosus, and Systemic Sclerosis: A Comparative Study of 150 Patients.Dermatology (Basel, Switzerland) · 2022Article
- Detection of microvascular changes in systemic sclerosis and other rheumatic diseases.Nature reviews. Rheumatology · 2021Review
- Article
- Nailfold Capillaroscopy Abnormalities Correlate With Disease Activity in Adult Dermatomyositis.Frontiers in medicine · 2021Article
- Nailfold Capillaroscopy With USB Digital Microscopy in Connective Tissue Diseases: A Comparative Study of 245 Patients and Healthy Controls.Frontiers in medicine · 2021Article
- Nailfold capillaroscopy in rheumatology: ready for the daily use but with care in terminology.Clinical rheumatology · 2019Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
objectivesIt is to prospectively analyze nailfold capillaroscopy (NC) findings in new-onset dermatomyositis (DM) and to correlate NC findings with serum angiogenic cytokines and DM clinical and laboratory features. MATERIALS AND
methodsTwenty-three patients with DM who experienced < 12 months of symptoms were included in the study. To assess serum cytokine levels, 23 age-, sex-, and ethnicity-matched healthy volunteers were used. NC characteristics and DM activity parameters were analyzed.
resultsSignificantly higher serum angiogenin (ANG) and vascular endothelial growth factor-1 (VEGF1) levels were observed in DM patients than in controls. Capillary density and avascular areas correlated positively and negatively, respectively, with serum levels of ANG. Moreover, the capillary density correlated inversely with the number of enlarged and giant capillaries and avascular areas. The number of enlarged capillaries correlated positively with patient and physician visual analogue scales (VAS), the presence of a facial rash, giant capillaries, and microhemorrhages. Giant capillaries had a positive correlation with physician and cutaneous VAS, enlarged capillaries, avascular areas, microhemorrhages and bushy capillaries, and a negative correlation with capillary density. Microhemorrhages correlated positively with the "V-neck" sign and physician VAS. VEGF1 showed no relationship with the NC parameters with DM-related clinical and laboratory features. Additionally, 15 out of 23 patients were assessed prospectively after 3.21 years. All patients had a major clinical response with significant improvement in all NC parameters, except for enlarged and bushy capillaries.
conclusionsThe NC may be a useful tool to assess disease activity in recent-onset DM, and it can also reinforce the role of ANG in the angiogenesis of this myopathy.
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