ArticleJournal of materials science. Materials in medicine2019
Improvements on biological and antimicrobial properties of titanium modified by AgNPs-loaded chitosan-heparin polyelectrolyte multilayers.
Article in Journal of materials science. Materials in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- Nano-Modified Titanium Implant Surfaces for the Prevention and Treatment of Peri-Implantitis: A Review.International journal of nanomedicine · 2026Review
- Enhanced peri-implantitis management through purple-LED irradiation coupled with silver ion application and calcium phosphate gene transfection carrier coating.Scientific reports · 2025Article
- Extraction, Purification, Characterization, Applications of Chitosan, Plant Gum Polysaccharides, and Other Polysaccharides: A Review.Scientifica · 2025Review
- Animal experiment on osseointegration of porous titanium root analogue implants with composite CSn-TAK242 coating.Frontiers in bioengineering and biotechnology · 2025Article
- Surface modification strategies to reinforce the soft tissue seal at transmucosal region of dental implants.Bioactive materials · 2024Review
- Recent advances in layer-by-layer assembly scaffolds for co-delivery of bioactive molecules for bone regeneration: an updated review.Journal of translational medicine · 2024Review
- Biomaterials science and surface engineering strategies for dental peri-implantitis management.Military Medical Research · 2024Review
- Biomimetic Coatings in Implant Dentistry: A Quick Update.Journal of functional biomaterials · 2023Review
- Functional engineering strategies of 3D printed implants for hard tissue replacement.Regenerative biomaterials · 2023Review
- Advanced materials and technologies for oral diseases.Science and technology of advanced materials · 2023Review
- Antibacterial and Cytocompatible: Combining Silver Nitrate with Strontium Acetate Increases the Therapeutic Window.International journal of molecular sciences · 2022Article
- The Antibacterial and Cytotoxic Effects of Silver Nanoparticles Coated Titanium Implants: A Narrative Review.Materials (Basel, Switzerland) · 2022Review
- Single-Step Process for Titanium Surface Micro- and Nano-Structuring and In Situ Silver Nanoparticles Formation by Ultra-Short Laser Patterning.Materials (Basel, Switzerland) · 2022Article
- A two-phase and long-lasting multi-antibacterial coating enables titanium biomaterials to prevent implants-related infections.Materials today. Bio · 2022Article
- Article
- Biomimetic Inorganic Nanoparticle-Loaded Silk Fibroin-Based Coating with Enhanced Antibacterial and Osteogenic Abilities.ACS omega · 2021Article
- Nanoparticles in Dentistry: A Comprehensive Review.Pharmaceuticals (Basel, Switzerland) · 2021Review
- Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microbial infection around dental implants is a major cause for the loss of devices, including soft tissue infection in early period, post-operation peri-implantitis, and osseointegration failure. Silver nanoparticles (AgNPs) with wide antimicrobial spectrum, strong antimicrobial effect and hypotoxicity, as well as low incidence of antibiotic resistance, are widely involved in biomedical applications. Herein, firmly anchoring AgNPs onto the surface of implants through physical-chemical reaction is likely to relieve the above issues. In this study, AgNPs were biosynthesized by a simple and "green" method with chitosan (CS) as stabilizing and reducing agents. Then, AgNPs-loaded CS-heparin polyelectrolyte multilayers (PEMs) were constructed on alkali-heat treated titanium (Ti) substrates via layer-by-layer (LbL) self-assembly technique. The successful surface modification could be confirmed by scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS), and the constructed system could provide the continuous release of Ag
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.