Evidence map›Paper›PMID 31016400›Full record

ArticleMikrochimica acta2019

Immunoassay for pathogenic bacteria using platinum nanoparticles and a hand-held hydrogen detector as transducer. Application to the detection of Escherichia coli O157:H7.

Sheng-Jun Bu, Kui-Yu Wang, Hua-Song Bai, Yan Leng, Chuan-Jing Ju, Cheng-Yu Wang, Wen-Sen Liu, Jia-Yu Wan

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Technologies for Frugal and Sensitive Point-of-Care Immunoassays.Annual review of analytical chemistry (Palo Alto, Calif.) · 2022
    Review
  5. Detection ofSensors (Basel, Switzerland) · 2022
    Article
  6. Article
  7. Article
  8. Point-of-care detection ofIranian journal of basic medical sciences · 2020
    Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Sheng-Jun BuInstitute of Military Veterinary, Academy of Military Medical Sciences, Changchun, 130122, China.
Kui-Yu WangInstitute of Military Veterinary, Academy of Military Medical Sciences, Changchun, 130122, China.
Hua-Song BaiInstitute of Military Veterinary, Academy of Military Medical Sciences, Changchun, 130122, China.
Yan LengInstitute of Military Veterinary, Academy of Military Medical Sciences, Changchun, 130122, China.
Chuan-Jing JuThe General Hospital of FAW, Changchun, 130011, China.
Cheng-Yu WangInstitute of Military Veterinary, Academy of Military Medical Sciences, Changchun, 130122, China.
Wen-Sen LiuInstitute of Military Veterinary, Academy of Military Medical Sciences, Changchun, 130122, China. Liuws85952@163.com.
Jia-Yu WanInstitute of Military Veterinary, Academy of Military Medical Sciences, Changchun, 130122, China. wanjiayu@hotmail.com.ORCID 0000-0002-1358-4143
Academy of Military Medical Sciences · CNJilin University · CN

Funding

National Key Research and Development Program of China 2016YFD0501001
6 · The paper itself

Abstract

An innovative approach is presented for portable and sensitive detection of pathogenic bacteria. A novel synthetic hybrid nanocomposite encapsulating platinum nanoparticles, as a highly efficient catalyst, catalyzes the hydrolysis of the ammonia-borane complex to generate hydrogen gas. The nanocomposites are used as a label for immunoassays. A portable hand-held hydrogen detector combined with nanocomposite-induced signal conversion was applied for point-of-care testing of pathogenic bacteria. A hand-held hydrogen detector was used as the transducer. Escherichia coli O157:H7 (E. coli O157: H7), as detection target, formed a sandwich structure with magnetic beads and hybrid nanocomposites. Magnetic beads were used for separation of the sandwich structure, and hybrid nanocomposites as catalysts to catalyze the generation of hydrogen from ammonia-borane. The generated hydrogen was detected by a hydrogen detector using an electrochemical method. E. coli O157:H7 has a detection limit of 10 CFU·mL

Indexed as

Hybrid nanocompositesHydrogen gasImmunosensorLODPlatinum nanoparticlesPoint-of-care

Identifiers

PMID31016400
OpenAlexW2941189231

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.