Evidence map›Paper›PMID 31016289›Full record

ArticleAnimal models and experimental medicine2019

A novel mouse model of adult T-cell leukemia cell invasion into the spinal cord.

Takeo Ohsugi, Shuhei Tanaka, Keigo Iwasaki, Yusuke Nagano, Tomohiro Kozako, Kazuya Matsuda, Takuya Hirose, Kazushige Takehana

Open access · diamondAbstract read
In one paragraph

Article in Animal models and experimental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Takeo OhsugiDepartment of Laboratory Animal Sciences School of Veterinary Medicine Rakuno Gakuen University Ebetsu Hokkaido Japan.ORCID https://orcid.org/0000-0002-7818-6840
Shuhei TanakaDepartment of Laboratory Animal Sciences School of Veterinary Medicine Rakuno Gakuen University Ebetsu Hokkaido Japan.
Keigo IwasakiDepartment of Laboratory Animal Sciences School of Veterinary Medicine Rakuno Gakuen University Ebetsu Hokkaido Japan.
Yusuke NaganoDepartment of Laboratory Animal Sciences School of Veterinary Medicine Rakuno Gakuen University Ebetsu Hokkaido Japan.
Tomohiro KozakoFaculty of Pharmaceutical Sciences Department of Biochemistry Fukuoka University Fukuoka Japan.
Kazuya MatsudaDepartment of Veterinary Pathology School of Veterinary Medicine Rakuno Gakuen University Ebetsu Hokkaido Japan.
Takuya HiroseDepartment of Veterinary Microanatomy School of Veterinary Medicine Rakuno Gakuen University Ebetsu Hokkaido Japan.
Kazushige TakehanaDepartment of Veterinary Microanatomy School of Veterinary Medicine Rakuno Gakuen University Ebetsu Hokkaido Japan.
Rakuno Gakuen University · JPFukuoka University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adult T-cell leukemia (ATL) is a mature T-cell malignancy caused by human T-cell leukemia virus type I infection, and 10%-25% of patients show central nervous system (CNS) involvement. CNS involvement significantly reduces survival and there are no effective treatments for CNS involvement. Therefore, an appropriate animal model is required to evaluate the inhibitory effects of novel drugs on the progression of ATL with CNS involvement. Here, we established a mouse model of ATL with CNS involvement using NOD.Cg-Prkdc

Indexed as

adult T‐cell leukemia (ATL)central nervous system (CNS)human T‐cell leukemia virus type I (HTLV‐1)miceNOD.Cg‐PrkdcscidIl2rgtm1Wjl/SzJ mice

Identifiers

PMID31016289
PMCPMC6431123
OpenAlexW2912621325

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.