Evidence map›Paper›PMID 31016168›Full record

ArticleIndian journal of endocrinology and metabolism

Uric Acid and Its Correlation with Various Metabolic Parameters: A Population-Based Study.

Pradip Mukhopadhyay, Sujoy Ghosh, Kaushik Pandit, Purushottam Chatterjee, Bikash Majhi, Subhankar Chowdhury

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of endocrinology and metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Pradip MukhopadhyayDepartment of Endocrinology, IPGME and R, Kolkata, West Bengal, India.
Sujoy GhoshDepartment of Endocrinology, IPGME and R, Kolkata, West Bengal, India.
Kaushik PanditDepartment of Endocrinology, Belle Vue Clinic, 9 Dr. U.N. Brahmachari Street, Kolkata, West Bengal, India.
Purushottam ChatterjeeDepartment of Endocrinology, Apollo Gleaneagles Hospital, 58 Canal Circular Road, Kolkata, West Bengal, India.
Bikash MajhiDepartment of Lifelong Learning and Extension, PSV, Visva-Bharati, Sriniketan, West Bengal, India.
Subhankar ChowdhuryDepartment of Endocrinology, IPGME and R, Kolkata, West Bengal, India.
Medical College and Hospital, Kolkata · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionUric acid, apparently an inert waste product, was found to have association with various metabolic disorders. The data regarding prevalence of serum uric acid (SUA) abnormalities and its correlation with other anthropo-metabolic parameters, however, are scanty. MATERIALS AND

methodsIn all, 405 participants from a rural area were investigated for various metabolic parameters including uric acid. SUA level was evaluated for having any correlation with other anthropometric and metabolic disorders like obesity, dyslipidemia, metabolic syndrome (MetS), hypertension, calcium and vitamin D abnormalities, liver function, and glycemic alterations. Lean MetS is defined as those having waist criteria below the region specific waist criteria and even then satisfying the definition of MetS as per the National Cholesterol Education Program (NCEP) ATP-III (Adult Treatment Panel) criteria.

resultsThe mean uric acid was 4.2 mg/dL (±1.35), with 4.9 mg/dL (±1.28) for males and 3.7 mg/dL (±1.14) for females. Thirteen of 405 people (3.2%) found to have uric acid level of more than 7.0 mg/dL, and eight people out of 405 (2.0%) had hypouricemia. SUA showed correlation with age, blood pressure, and the anthropometric parameters for obesity, for example, weight, body mass index, waist circumference, waist hip ratio, waist height ratio, fasting insulin, Homeostatic Model Assessment of Insulin Resistance (HOMA-IR), low-density lipoprotein (LDL)-cholesterol, high-density lipoprotein (HDL)-cholesterol, and triglycerides. However, fasting glucose, calcium, phosphate, 25-hydroxy vitamin D3, and iPTH did not show any correlation with the SUA level. Compared to the healthy population, SUA level was elevated in MetS as defined by International Diabetes Federation (IDF) criteria. However, the SUA in healthy population was not significantly different from the Lean MetS, and SUA of Lean MetS was not significantly different from Obese MetS.

conclusionSUA is elevated in MetS compared to the normal population. However, SUA in Lean MetS is not different from Obese MetS.

Indexed as

Lean metabolic syndromemetabolic syndromeuric acid

Identifiers

PMID31016168
PMCPMC6446663
OpenAlexW2921345635

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.