Evidence map›Paper›PMID 31015974›Full record

ArticleEcology and evolution2019

EasyCodeML: A visual tool for analysis of selection using CodeML.

Fangluan Gao, Chengjie Chen, Daej A Arab, Zhenguo Du, Yehua He, Simon Y W Ho

Abstract read
In one paragraph

Article in Ecology and evolution, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 281 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
281citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

281 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Characterization of Three Complete Mitochondrial Genomes ofInternational journal of molecular sciences · 2026
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  11. Cross-Species Sex Identification and Comparative Analysis of theAnimals : an open access journal from MDPI · 2026
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221 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fangluan GaoFujian Key Laboratory of Plant Virology, Institute of Plant Virology Fujian Agriculture and Forestry University Fuzhou China.ORCID https://orcid.org/0000-0001-9031-9944
Chengjie ChenCollege of Horticulture South China Agricultural University Guangzhou China.
Daej A ArabSchool of Life and Environmental Sciences University of Sydney Sydney New South Wales Australia.
Zhenguo DuFujian Key Laboratory of Plant Virology, Institute of Plant Virology Fujian Agriculture and Forestry University Fuzhou China.
Yehua HeCollege of Horticulture South China Agricultural University Guangzhou China.
Simon Y W HoSchool of Life and Environmental Sciences University of Sydney Sydney New South Wales Australia.ORCID https://orcid.org/0000-0002-0361-2307

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genomic signatures of positive selection and evolutionary constraints can be detected by analyses of nucleotide sequences. One of the most widely used programs for this purpose is CodeML, part of the PAML package. Although a number of bioinformatics tools have been developed to facilitate the use of CodeML, these have various limitations. Here, we present a wrapper tool named EasyCodeML that provides a user-friendly graphical interface for using CodeML. EasyCodeML has a custom running mode in which parameters can be adjusted to meet different requirements. It also offers a preset running mode in which an evolutionary analysis pipeline and publication-quality tables can be exported by a single click. EasyCodeML allows visualized, interactive tree labelling, which greatly simplifies the use of the branch, branch-site, and clade models of selection. The program allows comparison of major codon-based models for analyses of selection. EasyCodeML is a stand-alone package that is supported in Windows, Mac, and Linux operating systems, and is freely available at https://github.com/BioEasy/EasyCodeML.

Indexed as

CodeMLcodon‐based modelslikelihood‐ratio testmolecular evolutionpositive selection

Identifiers

PMID31015974
PMCPMC6467853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.