Evidence map›Paper›PMID 31015941›Full record

ArticleChemical science2019

Modular genetic design of multi-domain functional amyloids: insights into self-assembly and functional properties.

Mengkui Cui, Qi Qi, Thomas Gurry, Tianxin Zhao, Bolin An, Jiahua Pu, Xinrui Gui, Allen A Cheng, Siyu Zhang, Dongmin Xun and 5 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

  1. De Novo Autogenic Engineered Living Functional Materials.Advanced materials (Deerfield Beach, Fla.) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 5 countries.

Mengkui CuiSchool of Physical Science and Technology , ShanghaiTech University , Shanghai 200120 , China . Email: zhongchao@shanghaitech.edu.cn.
Qi QiSchool of Physical Science and Technology , ShanghaiTech University , Shanghai 200120 , China . Email: zhongchao@shanghaitech.edu.cn.
Thomas GurryDepartment of Biological Engineering , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139-4307 , USA.ORCID 0000-0002-8639-1860
Tianxin ZhaoSchool of Physical Science and Technology , ShanghaiTech University , Shanghai 200120 , China . Email: zhongchao@shanghaitech.edu.cn.
Bolin AnSchool of Physical Science and Technology , ShanghaiTech University , Shanghai 200120 , China . Email: zhongchao@shanghaitech.edu.cn.
Jiahua PuSchool of Physical Science and Technology , ShanghaiTech University , Shanghai 200120 , China . Email: zhongchao@shanghaitech.edu.cn.
Xinrui GuiShanghai Institute of Organic Chemistry , Chinese Academy of Sciences , Shanghai 200032 , China.
Allen A ChengDepartment of Electrical Engineering and Computer Science , Department of Biological Engineering , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139-4307 , USA.
Siyu ZhangSchool of Physical Science and Technology , ShanghaiTech University , Shanghai 200120 , China . Email: zhongchao@shanghaitech.edu.cn.
Dongmin XunSchool of Physical Science and Technology , ShanghaiTech University , Shanghai 200120 , China . Email: zhongchao@shanghaitech.edu.cn.
Michele BecceDepartment of Electrical Engineering and Computer Science , Department of Biological Engineering , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139-4307 , USA.ORCID 0000-0002-8800-6954
Francesco Briatico-VangosaDipartimento di Chimica Materiali e Ingegneria Chimica G. Natta , Politecnico di Milano , Piazza Leonardo da Vinci 32 , 20133 Milano , Italy.ORCID 0000-0002-7088-1064
Cong LiuInterdisciplinary Research Center on Biology and Chemistry , Shanghai Institute of Organic Chemistry , Chinese Academy of Sciences , Shanghai 200032 , China.
Timothy K LuDepartment of Electrical Engineering and Computer Science , Department of Biological Engineering , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139-4307 , USA.
Chao ZhongSchool of Physical Science and Technology , ShanghaiTech University , Shanghai 200120 , China . Email: zhongchao@shanghaitech.edu.cn.ORCID 0000-0002-6638-3652
ShanghaiTech University · CNChinese Academy of Sciences · CNMassachusetts Institute of Technology · USImperial College London · GBMylan (South Africa) · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Engineering functional amyloids through a modular genetic strategy represents new opportunities for creating multifunctional molecular materials with tailored structures and performance. Despite important advances, how fusion modules affect the self-assembly and functional properties of amyloids remains elusive. Here, using

Identifiers

PMID31015941
PMCPMC6461117
OpenAlexW2915025993

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.