ArticleChemical science2019
Evaluation of HOCl-generating anticancer agents by an ultrasensitive dual-mode fluorescent probe.
Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 115 citations in OpenAlex.
- A NIR-IIb-excited capsule endoscope enabling high-contrast fluorescence imaging via spectrally-isolated detection for early-stage gastrointestinal cancer.Journal of nanobiotechnology · 2026Article
- Dual-responsive bis-Schiff base fluorescent probe for simultaneous detection of ZnScientific reports · 2025Article
- Diaminomaleonitrile Schiff Base Probe for the Detection of Copper Ions in a Semi-Aqueous Medium and its Applications.Journal of fluorescence · 2025Article
- A novel multifunctional fluorescent probe with ESIPT and AIE effects for the detection of CoRSC advances · 2025Article
- A ratiometric near-infrared fluorescent probe for the detection and monitoring of hypochlorous acid in rheumatoid arthritis model and real water samples.Smart molecules : open access · 2023Article
- Crystal structure of 3-(benzo[Acta crystallographica. Section E, Crystallographic communications · 2023Article
- A Hydroxytricyanopyrrole-Based Fluorescent Probe for Sensitive and Selective Detection of Hypochlorous Acid.Molecules (Basel, Switzerland) · 2022Article
- The Development of a 4-aminonaphthalimide-based Highly Selective Fluorescent Probe for Rapid Detection of HOCl.Journal of fluorescence · 2022Article
- Rational construction of deep-red fluorescent probe for rapid detection of HClO and its application in bioimaging and paper-based sensing.Analytical and bioanalytical chemistry · 2022Article
- Surfactant-free synthesis of fluorescent platinum nanoclusters using HEPES buffer for hypochlorous acid sensing and imaging.RSC advances · 2022Article
- 3-(Benzo[IUCrData · 2022Article
- A Highly Selective Fluorescent Probe for Hypochlorous Acid in Living Cells Based on a Naphthalene Derivative.International journal of analytical chemistry · 2022Article
- Stress response decay with aging visualized using a dual-channel logic-based fluorescent probe.Chemical science · 2021Article
- A Sensitive and Selective Fluorescent Probe for Real-Time Detection and Imaging of Hypochlorous Acid in Living Cells.ACS omega · 2021Article
- A naphthalimide-based turn-on fluorescence probe for peroxynitrite detection and imaging in living cells.RSC advances · 2020Article
- Review
- Reaction-Based Fluorescent Probes for the Detection and Imaging of Reactive Oxygen, Nitrogen, and Sulfur Species.Accounts of chemical research · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypochlorous acid (HOCl), a reactive oxygen species (ROS), plays a crucial role in the process of pathogenic oxidative stress. Some powerful anticancer agents, such as elesclomol, specifically induce cancer cell apoptosis by increasing HOCl levels. However, sensitive tools to monitor subtle changes of biological HOCl
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.