Evidence map›Paper›PMID 31015859›Full record

Observational studyWorld journal of emergency surgery : WJES2019

Damage control surgery for perforated diverticulitis with diffuse peritonitis: saves lives and reduces ostomy.

Dario Tartaglia, Gianluca Costa, Antonio Camillò, Maurizio Castriconi, Mauro Andreano, Michele Lanza, Pietro Fransvea, Paolo Ruscelli, Massimiliano Rimini, Christian Galatioto and 1 more

Registry-linked trialOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in World journal of emergency surgery : WJES, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06428370 (An International Study Investigating the Adoption and Outcome of Damage Control Surgery in Hinchey III-IV Acute Diverticulitis), which is not on this map. Cited by 27 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 6 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06428370 unknown statusnot on this mapstarted 2020, after this paper: background citation

An International Study Investigating the Adoption and Outcome of Damage Control Surgery in Hinchey III-IV Acute Diverticulitis (DACOSAD)

TypeobservationalSponsorLink Campus UniversityRan2020 to 2025Enrolled300ConditionsDiverticular Perforation, Open AbdomenArmsDamage Control Surgery
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 6 syntheses or guidelines pooled it, 51 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Dario Tartaglia1Emergency Surgery Unit, New Santa Chiara Hospital, University of Pisa, Via Paradisa 2, 56124 Pisa, Italy.ORCID 0000-0003-1615-3370
Gianluca Costa2Emergency Surgery Unit, Sant'Andrea Teaching Hospital, University Sapienza, Rome, Italy.
Antonio Camillò1Emergency Surgery Unit, New Santa Chiara Hospital, University of Pisa, Via Paradisa 2, 56124 Pisa, Italy.
Maurizio Castriconi3Emergency Surgery Unit, Ospedale Cardarelli, Naples, Italy.
Mauro Andreano3Emergency Surgery Unit, Ospedale Cardarelli, Naples, Italy.
Michele Lanza3Emergency Surgery Unit, Ospedale Cardarelli, Naples, Italy.
Pietro Fransvea2Emergency Surgery Unit, Sant'Andrea Teaching Hospital, University Sapienza, Rome, Italy.
Paolo Ruscelli4Emergency Surgery Unit, Ospedali Riuniti Teaching Hospital, Polytechnic University of Marche, Ancona, Italy.
Massimiliano Rimini4Emergency Surgery Unit, Ospedali Riuniti Teaching Hospital, Polytechnic University of Marche, Ancona, Italy.
Christian Galatioto1Emergency Surgery Unit, New Santa Chiara Hospital, University of Pisa, Via Paradisa 2, 56124 Pisa, Italy.
Massimo Chiarugi1Emergency Surgery Unit, New Santa Chiara Hospital, University of Pisa, Via Paradisa 2, 56124 Pisa, Italy.
University of Pisa · ITOspedale Antonio Cardarelli · ITAzienda Ospedaliera Sant'Andrea · ITMarche Polytechnic University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Over the last decade, damage control surgery (DCS) has been emerging as a feasible alternative for the management of patients with abdominal infection and sepsis. So far, there is no consensus about the role of DCS for acute perforated diverticulitis. In this study, we present the outcome of a multi-institutional series of patients presenting with Hinchey's grade III and IV diverticulitis managed by DCS. Methods: All the participating centers were tertiary referral hospitals. A total of 34 patients with perforated diverticulitis treated with DCS during the period 2011-2017 were included in the study. During the first laparotomy, a limited resection of the diseased segment was performed followed by lavage and use of negative pressure wound therapy (NPWT). After 24/48 h of resuscitation, patients returned to the operating room for a second look. Mortality, morbidity, and restoration of bowel continuity were the primary outcomes of the study. Results: There were 15 males (44%) and 19 females (56%) with a mean age of 66.9 years (SD ± 12.7). Mean BMI was 28.42 kg/m Conclusion: DCS is a feasible procedure for patients with generalized peritonitis secondary to perforated diverticulitis, and it appears to be related to a higher rate of bowel reconstruction. Due to the open abdomen, stay in ICU with prolonged mechanical ventilation is required, but these aggressive measures may be needed by most patients undergoing surgery for perforated diverticulitis, whatever the procedure is done.

Indexed as

AdultAgedDigestive System Surgical ProceduresDiverticulitis, ColonicFemaleHumansIntestinal PerforationMaleMiddle AgedOstomyPeritonitisRetrospective StudiesStatistics, NonparametricTreatment OutcomeComplicated diverticulitisDamage control surgeryObservational study

Identifiers

PMID31015859
PMCPMC6469209
OpenAlexW2945950121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.