ArticleClinical practice and epidemiology in mental health : CP & EMH2019
Sex-Related Differences in Plasma Oxytocin Levels in Humans.
Article in Clinical practice and epidemiology in mental health : CP & EMH, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed, 73 citations in OpenAlex.
- Feasibility study examining the short-term effects of Sonic Augmentation Technology™.Frontiers in psychiatry · 2026Trial
- Temporal profile of intranasal oxytocin in the human autonomic nervous system at rest: An electrocardiography and pupillometry study.Journal of psychopharmacology (Oxford, England) · 2023Trial
- Genetic and epigenetic signatures associated with plasma oxytocin levels in children and adolescents with autism spectrum disorder.Autism research : official journal of the International Society for Autism Research · 2023Trial
- Clinical Phenotypes and Neurobiology of Youth With Avoidant/Restrictive Food Intake Disorder (ARFID) Across Sex.The International journal of eating disorders · 2026Article
- Comment on: Oxytocin: a neglected hormone in pituitary disease - From function to the diagnosis of a deficiency, resulting clinical relevance, and potential treatment options in endocrinology.Archives of endocrinology and metabolism · 2026Article
- Oxytocin agonist TGOT differentially modulates synaptic plasticity and intrinsic excitability in a sex-specific manner in the juvenile rat hippocampus.Communications biology · 2026Article
- Fracture risks in patients with arginine vasopressin deficiency: a nationwide matched cohort study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- Article
- Oxytocin levels do not change around a meal and correlate with reward-driven caloric consumption in adults with obesity.Diabetes, obesity & metabolism · 2026Article
- Oxytocin, Weight Loss and Ketosis in Response to a Very-Low-Calorie Ketogenic Diet: An Exploratory Study.Nutrients · 2026Article
- Checking assumptions: advancing the analysis of sex and gender in health sciences.Biology of sex differences · 2026Review
- Sex-dimorphic oxytocin regulation of CA1-dependent spatial memory and synaptic plasticity in juvenile rats.Behavioral and brain functions : BBF · 2025Article
- Oxytocin significantly enhances GABAergic transmission in the central amygdala of alcohol-naïve and alcohol-dependent female rats.Neuropharmacology · 2025Article
- Neuropeptides, Altruism, and Adverse Childhood Experiences: Investigating Biological and Behavioral Correlations in Medical Students.Brain sciences · 2025Article
- Epidemiology of adult separation anxiety disorder in the Kingdom of Saudi Arabia: results from the Saudi National Mental Health Survey.Social psychiatry and psychiatric epidemiology · 2025Article
- Review
- The Oxytocin System and Implications for Oxytocin Deficiency in Hypothalamic-Pituitary Disease.Endocrine reviews · 2025Review
- Charting Salivary Oxytocin Across an Episode of Naturally Occurring Partnered Sex.Archives of sexual behavior · 2025Article
- Trajectories of changes in oxytocin and vasopressin before, during, and after mother-infant interaction: a descriptive study of mothers and infants affected by postpartum depression.Frontiers in psychiatry · 2025Article
- The association between salivary oxytocin, age, and puberty in children with and without OCD.Scientific reports · 2024Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIncreasing evidence supports a key role of Oxytocin (OT) as a modulator of social relationships in mammals.
objectiveThe aim of the present study was to investigate possible sex-related differences in plasma OT levels in human beings.
methodsForty-five healthy men and 45 women (mean age: 34.9 ± 6.2 years), were included in the study. Plasma preparation, peptide extraction and OT radioimmunoassay were carried out according to standardized methods.
resultsThe results showed that OT plasma levels (pg / ml, mean ± SD) were significantly higher in women than in men (4.53 ± 1.18 vs 1.53 ± 1.19, p ˂ 0.001).
conclusionsThe present finding demonstrates sex-related differences in plasma OT levels in humans. It is tempting to hypothesize that such differences might be related to behaviours, attitudes, as well as susceptibility to stress response, resilience and social emotions specific of women and men.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.