Evidence map›Paper›PMID 31015806›Full record

ArticleCanada communicable disease report = Releve des maladies transmissibles au Canada2018

Do health care providers trust product monograph information regarding use of vaccines in pregnancy? A qualitative study.

K A Top, C Arkell, J E Graham, H Scott, S A McNeil, J Mannerfeldt, N E MacDonald

Open access · diamondAbstract read
In one paragraph

Article in Canada communicable disease report = Releve des maladies transmissibles au Canada, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

K A TopDepartment of Pediatrics, Dalhousie University, Halifax, NS.
C ArkellSchool of Population and Public Health, University of British Columbia, Vancouver, BC.
J E GrahamDepartment of Pediatrics, Dalhousie University, Halifax, NS.
H ScottDepartment of Obstetrics & Gynecology, Dalhousie University, Halifax, NS.
S A McNeilCanadian Center for Vaccinology, Dalhousie University, IWK Health Centre, Nova Scotia Health Authority, Halifax, NS.
J MannerfeldtDepartments of Obstetrics & Gynecology and Family Medicine, University of Calgary, Calgary, AB.
N E MacDonaldDepartment of Pediatrics, Dalhousie University, Halifax, NS.
Izaak Walton Killam Health Centre · CANova Scotia Health Authority · CADalhousie University · CAUniversity of British Columbia · CAUniversity of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfluenza immunization is recommended in pregnancy to prevent severe infections in pregnant women and newborns, yet vaccine uptake remains low. Studies suggest that cautionary language in vaccine product monographs regarding safety and use in pregnancy affects health care providers' perceptions of vaccine safety and how they counsel pregnant women.

objectiveTo conduct a qualitative analysis of health care provider perceptions of the safety of inactivated influenza vaccines and their recommendations for use in pregnancy based on product monograph language statements.

methodsHealth care providers were recruited at two international health conferences and from teaching programs in Ethiopia, Ghana, Uganda, and Laos during September and October 2015. After reading the product monograph excerpts for three licensed inactivated influenza vaccines, participants completed a ten-item online survey with quantitative and qualitative components that captured perceptions of vaccine safety.

resultsHealth care providers identified a lack of trust in manufacturers' and product monograph information. They perceived product monograph language as ambiguous and not "up-to-date" with current evidence. Health care providers wanted product monograph language that clearly conveyed evidence for the risks and benefits of the vaccine in an understandable manner.

conclusionThis study suggests that adopting best practices in the wording of product monographs would help to support evidence-based use of vaccines in pregnant women.

Indexed as

pregnancyproduct monographsqualitative studyvaccines

Identifiers

PMID31015806
PMCPMC6449106
OpenAlexW2890418757

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.