Evidence map›Paper›PMID 31015794›Full record

ArticleMediators of inflammation2019

High-Fat Diet Alters Immunogenic Properties of Circulating and Adipose Tissue-Associated Myeloid-Derived CD45

Sara J Sidles, Ying Xiong, M Rita I Young, Amanda C LaRue

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. 'Youthful' phenotype of c-KitCellular and molecular life sciences : CMLS · 2022
    Article
  2. Review
  3. Article
  4. Review
  5. Single-cell RNA sequencing reveals the induction of novel myeloid and myeloid-associated cell populations in visceral fat with long-term obesity.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sara J SidlesResearch Services, Ralph H. Johnson VA Medical Center, Charleston, SC 29401, USA.ORCID 0000-0001-7177-0270
Ying XiongResearch Services, Ralph H. Johnson VA Medical Center, Charleston, SC 29401, USA.
M Rita I YoungResearch Services, Ralph H. Johnson VA Medical Center, Charleston, SC 29401, USA.
Amanda C LaRueResearch Services, Ralph H. Johnson VA Medical Center, Charleston, SC 29401, USA.ORCID 0000-0003-4572-1496
Medical University of South Carolina · US

Funding

Translational Science Laboratory Shared ResourceP30CA138313 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Jian Ouyang · 2009 to 2026
$42.7M
Hematopoietic Stem Cell-Derived Carcinoma Associated Fibroblasts in TumorR01CA148772 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI LARUE, AMANDA C. · 2011 to 2015
$1.3M
Potential of Hematopoietic Stem Cell-Based Therapies for Complicated FracturesI01BX000333 · VA · RALPH H JOHNSON VA MEDICAL CENTER · PI LARUE, AMANDA C. · 2009 to 2022
–
Targeting HSC-derived Circulating Fibroblast Precursors in Pulmonary FibrosisI01BX002277 · VA · RALPH H JOHNSON VA MEDICAL CENTER · PI LARUE, AMANDA C. · 2014 to 2017
–
BLRD VA I01 BX000333BLRD VA I01 BX002277NCI NIH HHS P30 CA138313NCI NIH HHS R01 CA148772
6 · The paper itself

Abstract

Chronic inflammation is evident in the adipose tissue and periphery of patients with obesity, as well as mouse models of obesity. T cell subsets in obese adipose tissue are skewed towards Th1- and Th17-associated phenotypes and their secreted cytokines contribute to obesity-associated inflammation. Our lab recently identified a novel, myeloid-derived CD45

Indexed as

Adipose TissueAnimalsCD4-Positive T-LymphocytesCells, CulturedDiet, High-FatDiscoidin Domain Receptor 2FemaleFlow CytometryLeukocyte Common AntigensMiceMice, Inbred C57BLDdr2 protein, mouseDiscoidin Domain Receptor 2Leukocyte Common Antigens

Identifiers

PMID31015794
PMCPMC6421777
OpenAlexW2920516910

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.