Evidence map›Paper›PMID 31015542›Full record

ArticleScientific reports2019

Ancient amino acids from fossil feathers in amber.

Victoria E McCoy, Sarah E Gabbott, Kirsty Penkman, Matthew J Collins, Samantha Presslee, John Holt, Harrison Grossman, Bo Wang, Monica M Solórzano Kraemer, Xavier Delclòs and 1 more

Open access · goldAbstract readHistorical Article
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
46.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 145 citations in OpenAlex.

  1. Article
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  4. Insights into the early evolution of modern avian physiology from fossilized soft tissues from the Mesozoic.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  5. Preservation of proteins in the geosphere.Nature ecology & evolution · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 5 countries.

Victoria E McCoySteinmann-Institut für Geologie, Mineralogie und Paläontologie, Universität Bonn, Nussallee 8, 53115, Bonn, Germany. vmccoy@uni-bonn.de.
Sarah E GabbottSchool of Geography, Geology, and the Environment, University of Leicester, University Road, Leicester, LE1 7RH, UK.
Kirsty PenkmanDepartment of Chemistry, University of York, Heslington, York, YO10 5DD, UK.
Matthew J CollinsBioArCh, Department of Archaeology, University of York, York, YO10 5DD, UK.ORCID http://orcid.org/0000-0003-4226-5501
Samantha PressleeBioArCh, Department of Archaeology, University of York, York, YO10 5DD, UK.
John HoltSpace Research Centre, Department of Physics and Astronomy, University of Leicester, University Road, Leicester, LE1 7RH, UK.
Harrison GrossmanSpace Research Centre, Department of Physics and Astronomy, University of Leicester, University Road, Leicester, LE1 7RH, UK.
Bo WangState Key Laboratory of Palaeobiology and Stratigraphy, Nanjing Institute of Geology and Palaeontology and Center for Excellence in Life and Paleoenvironment, Chinese Academy of Sciences, 39 East Beijing Road, Nanjing, 210008, China.ORCID http://orcid.org/0000-0002-8001-9937
Monica M Solórzano KraemerSenckenberg Forschungsinstitut und Naturmuseum, Paläontologie und Historische Geologie, Senckenberganlage 25, 60325, Frankfurt am Main, Germany.
Xavier DelclòsDepartment Dinàmica de la Terra i de l'Oceà, Facultat de Ciències de la Terra, and Institut de Recerca da la Biodiversitat (IRBio), Universitat de Barcelona, 08028, Barcelona, Spain.ORCID http://orcid.org/0000-0002-2233-5480
Enrique PeñalverInstituto Geológico y Minero de España (Museo Geominero), C/Cirilo Amorós, 42-46004, Valencia, Spain.
University of Leicester · GBUniversity of York · GBChinese Academy of Sciences · CNInstituto Geológico y Minero de España · ESNatural History Museum Aarhus · DKSenckenberg Research Institute and Natural History Museum Frankfurt/M · DEUniversitat de Barcelona · ESUniversity of Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ancient protein analysis is a rapidly developing field of research. Proteins ranging in age from the Quaternary to Jurassic are being used to answer questions about phylogeny, evolution, and extinction. However, these analyses are sometimes contentious, and focus primarily on large vertebrates in sedimentary fossilisation environments; there are few studies of protein preservation in fossils in amber. Here we show exceptionally slow racemisation rates during thermal degradation experiments of resin enclosed feathers, relative to previous thermal degradation experiments of ostrich eggshell, coral skeleton, and limpet shell. We also recover amino acids from two specimens of fossil feathers in amber. The amino acid compositions are broadly similar to those of degraded feathers, but concentrations are very low, suggesting that much of the original protein has been degraded and lost. High levels of racemisation in more apolar, slowly racemising amino acids suggest that some of the amino acids were ancient and therefore original. Our findings indicate that the unique fossilisation environment inside amber shows potential for the recovery of ancient amino acids and proteins.

Indexed as

AmberAmino AcidsAnimalsBirdsChromatography, Reverse-PhaseDinosaursEgg ShellExtinction, BiologicalFeathersFossilsHistory, AncientPreservation, BiologicalProteinsProteolysisAmberAmino AcidsProteins

Identifiers

PMID31015542
PMCPMC6478714
OpenAlexW2941236146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.