Evidence map›Paper›PMID 31015528›Full record

ArticleScientific reports2019

Comparative transcriptome analysis reveals the genetic basis of coat color variation in Pashmina goat.

Basharat Bhat, Ashutosh Singh, Zaffar Iqbal, Jai K Kaushik, A R Rao, Syed Mudasir Ahmad, Hina Bhat, Aadil Ayaz, F D Sheikh, Shalini Kalra and 5 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Genome-wide selective sweep analysis in high-altitude Changthangi goats reveals candidate genes for pashmina fiber production.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Article
  3. Animals : an open access journal from MDPI · 2025
    Article
  4. Review
  5. Deciphering the molecular drivers for cashmere/pashmina fiber production in goats: a comprehensive review.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Molecular insights into Pashmina fiber production: comparative skin transcriptomic analysis of Changthangi goats and sheep.Mammalian genome : official journal of the International Mammalian Genome Society · 2024
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Analysis ofAnimals : an open access journal from MDPI · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Basharat BhatDepartment of Life Science, Shiv Nadar University, Gautam Buddha Nagar, UP, 201314, India.ORCID http://orcid.org/0000-0002-4148-1694
Ashutosh SinghDepartment of Life Science, Shiv Nadar University, Gautam Buddha Nagar, UP, 201314, India.
Zaffar IqbalDivision of Animal Genetics and Breeding, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir, Shuhama, Jammu and Kashmir, 190016, India.
Jai K KaushikAnimal Biotechnology Centre, National Dairy Research Institute, Karnal, India.
A R RaoCentre for Agricultural Bioinformatics, Indian Agricultural Statistics Research Institute, New Delhi, India.
Syed Mudasir AhmadDivision of Animal Biotechnology, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir, Shuhama, Jammu and Kashmir, 190016, India.
Hina BhatDivision of Animal Biotechnology, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir, Shuhama, Jammu and Kashmir, 190016, India.
Aadil AyazDivision of Animal Genetics and Breeding, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir, Shuhama, Jammu and Kashmir, 190016, India.
F D SheikhDivision of Animal Genetics and Breeding, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir, Shuhama, Jammu and Kashmir, 190016, India.
Shalini KalraAnimal Biotechnology Centre, National Dairy Research Institute, Karnal, India.
Syed ShanazDivision of Animal Genetics and Breeding, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir, Shuhama, Jammu and Kashmir, 190016, India.
Masood Salim MirDivision of Animal Genetics and Breeding, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir, Shuhama, Jammu and Kashmir, 190016, India.
Pawan Kumar AgarwalIndian Council of Agricultural Research, New Delhi, India.
Trilochan MohapatraIndian Council of Agricultural Research, New Delhi, India.
Nazir A GanaiDivision of Animal Genetics and Breeding, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir, Shuhama, Jammu and Kashmir, 190016, India. naganai@skuastkashmir.ac.in.
Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir · INIndian Council of Agricultural Research · INNational Dairy Research Institute · INShiv Nadar University · INIndian Agricultural Statistics Research Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genetics of coat color variation remains a classic area. Earlier studies have focused on a limited number of genes involved in color determination; however, the complete set of trait determinants are still not well known. In this study, we used high-throughput sequencing technology to identify and characterize intricate interactions between genes that cause complex coat color variation in Changthangi Pashmina goats, producer of finest and costly commercial animal fiber. We systematically identified differentially expressed mRNAs and lncRNAs from black, brown and white Pashmina goat skin samples by using RNA-sequencing technique. A pairwise comparison of black, white and brown skin samples yielded 2479 significantly dysregulated genes (2422 mRNA and 57 lncRNAs). Differentially expressed genes were enriched in melanin biosynthesis, melanocyte differentiation, developmental pigmentation, melanosome transport activities GO terms. Our analysis suggested the potential role of lncRNAs on color coding mRNAs in cis and trans configuration. We have also developed online data repository as a component of the study to provide a central location for data access, visualization and interpretation accessible through http://pcd.skuastk.org/ .

Indexed as

Gene Expression ProfilingAnimalsGene Expression RegulationGene OntologyGenomeGoatsReproducibility of ResultsRNA, Long NoncodingRNA, MessengerSkin PigmentationTranscriptomeUser-Computer InterfaceRNA, Long NoncodingRNA, Messenger

Identifiers

PMID31015528
PMCPMC6478727
OpenAlexW2941196652

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.