ArticleNature communications2019
A clinically translatable hyperspectral endoscopy (HySE) system for imaging the gastrointestinal tract.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 3 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
56 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Medical hyperspectral imaging: an updated review of technology advancements and biomedical applications.Journal of biomedical optics · 2026Pooled it
- Hyperspectral imaging for tumor resection guidance in surgery: a systematic review of preclinical and clinical studies.Journal of biomedical optics · 2025Pooled it
- Noninvasive hemoglobin sensing and imaging: optical tools for disease diagnosis.Journal of biomedical optics · 2022Pooled it
- Endoscopic multispectral imaging sensor systems for intraoperative tissue differentiation.Journal of biomedical optics · 2026Article
- Deep Learning-Assisted Accuracy Improvement in Bladder Cancer Staging of Spectrum-Aided Visual Enhanced Cystoscopy Images.Biosensors · 2026Article
- Article
- Hyperspectral reconstruction of white light endoscopy images for enhanced segmentation of early esophageal lesions in patients.iScience · 2026Article
- Multi-contrast laser endoscopy for in vivo gastrointestinal imaging.Npj imaging · 2026Article
- Perspective on the current state of hyperspectral/multispectral imaging for minimally invasive surgery.Journal of biomedical optics · 2026Review
- Real-Time High-Definition Hyperspectral Endoscopy via Spatial-Temporal Low-Frequency-Stochastic Spectral Encoding.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Challenges and Prospects of Using Novel Nonlinear Effects in Multimode Optical Fibers for Multiphoton Endomicroscopy.Diagnostics (Basel, Switzerland) · 2026Review
- Development of a multiparameter phantom system for multispectral imaging.Biomedical optics express · 2025Article
- Development of a digital micromirror device-based hyperspectral imaging system with dynamically adjustable measurement regions.Scientific reports · 2025Article
- LED-based, real-time, hyperspectral imaging device.Journal of medical imaging (Bellingham, Wash.) · 2025Article
- Multimodal esophageal cancer imaging: establishing data processing techniques and assessing diagnostic sensitivity.Biophotonics discovery · 2025Article
- Small intestinal bleeding prediction by spectral reconstruction through band selection.Journal of biomedical optics · 2025Article
- Exploration of oral microbiota alteration and AI-driven non-invasive hyperspectral imaging for CAD prediction.BMC cardiovascular disorders · 2025Article
- Evaluating Normalization Methods for Robust Spectral Performance Assessments of Hyperspectral Imaging Cameras.Biosensors · 2025Article
- A novel flexible near-infrared endoscopic device that enables real-time artificial intelligence fluorescence tissue characterization.PloS one · 2025Article
- In-vivo non-contact multispectral oral disease image dataset with segmentation.Scientific data · 2024Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Hyperspectral imaging (HSI) enables visualisation of morphological and biochemical information, which could improve disease diagnostic accuracy. Unfortunately, the wide range of image distortions that arise during flexible endoscopy in the clinic have made integration of HSI challenging. To address this challenge, we demonstrate a hyperspectral endoscope (HySE) that simultaneously records intrinsically co-registered hyperspectral and standard-of-care white light images, which allows image distortions to be compensated computationally and an accurate hyperspectral data cube to be reconstructed as the endoscope moves in the lumen. Evaluation of HySE performance shows excellent spatial, spectral and temporal resolution and high colour fidelity. Application of HySE enables: quantification of blood oxygenation levels in tissue mimicking phantoms; differentiation of spectral profiles from normal and pathological ex vivo human tissues; and recording of hyperspectral data under freehand motion within an intact ex vivo pig oesophagus model. HySE therefore shows potential for enabling HSI in clinical endoscopy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.