Evidence map›Paper›PMID 31015334›Full record

ArticlemBio2019

Stable and Highly Immunogenic MicroRNA-Targeted Single-Dose Live Attenuated Vaccine Candidate against Tick-Borne Encephalitis Constructed Using Genetic Backbone of Langat Virus.

Konstantin A Tsetsarkin, Olga A Maximova, Guangping Liu, Heather Kenney, Natalya L Teterina, Alexander G Pletnev

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Langat Virus Biology and Infection.Reviews in medical virology · 2026
    Review
  2. Animal virus-host interactions mediated by non-coding RNAs.Frontiers in cellular and infection microbiology · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Tick-Borne Encephalitis (TBE): From Tick to Pathology.Journal of clinical medicine · 2023
    Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Konstantin A TsetsarkinLaboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Maryland, USA.
Olga A MaximovaLaboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Maryland, USA.
Guangping LiuLaboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Maryland, USA.
Heather KenneyLaboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Maryland, USA.
Natalya L TeterinaLaboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Maryland, USA.
Alexander G PletnevLaboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Maryland, USA apletnev@niaid.nih.gov.
National Institute of Allergy and Infectious Diseases · USNational Institutes of Health · US

Funding

Development Of New Approaches To Vaccines Against TBEV and West Nile VirusZIAAI000637 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI PLETNEV, ALEXANDER · 2009 to 2022
$19.1M
6 · The paper itself

Abstract

Tick-borne encephalitis virus (TBEV), a member of the genus

Indexed as

Drug CarriersGenetic VectorsAnimalsAntibodies, NeutralizingAntibodies, ViralChlorocebus aethiopsEncephalitis, Tick-BorneEncephalitis Viruses, Tick-BorneMiceMicroRNAsVaccines, AttenuatedVaccines, SyntheticVero CellsViral VaccinesVirus ReplicationAntibodies, NeutralizingAntibodies, ViralDrug CarriersMicroRNAsVaccines, AttenuatedVaccines, SyntheticViral Vaccineschimeric virusLangat viruslive attenuated virus vaccinemicroRNAtick-borne encephalitis virus

Identifiers

PMID31015334
PMCPMC6479010
OpenAlexW2937219782

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.