Evidence map›Paper›PMID 31015327›Full record

ArticlemBio2019

Dynamics of Mycobacterium tuberculosis Ag85B Revealed by a Sensitive Enzyme-Linked Immunosorbent Assay.

Joel D Ernst, Amber Cornelius, Miriam Bolz

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. HowVaccines · 2026
    Review
  2. Article
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  15. Article
  16. Enhancement of CD4Frontiers in cellular and infection microbiology · 2021
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Joel D ErnstDivision of Experimental Medicine, University of California, San Francisco, San Francisco, California, USA joel.ernst@ucsf.edu.
Amber CorneliusDivision of Infectious Diseases and Immunology, Department of Medicine, New York University School of Medicine, New York, New York, USA.
Miriam BolzDivision of Infectious Diseases and Immunology, Department of Medicine, New York University School of Medicine, New York, New York, USA.
New York University · US

Funding

Initiation of the Immune Response to M. tuberculosisR01AI051242 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ERNST, JOEL D. · 2002 to 2019
$8.3M
Antigen export in M. tuberculosis evasion of CD4 T cellsR01AI124471 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ERNST, JOEL D. · 2016 to 2019
$2.7M
NIAID NIH HHS R01 AI051242NIAID NIH HHS R01 AI124471
6 · The paper itself

Abstract

Secretion of specific proteins contributes to pathogenesis and immune responses in tuberculosis and other bacterial infections, yet the kinetics of protein secretion and fate of secreted proteins

Indexed as

AcyltransferasesAnimalsAntigens, BacterialBacterial ProteinsDisease Models, AnimalEnzyme-Linked Immunosorbent AssayLungMiceMycobacterium tuberculosisTuberculosis, PulmonaryAcyltransferasesantigen 85B, Mycobacterium tuberculosisAntigens, BacterialBacterial ProteinsAg85Bbacterial antigenbacterial protein secretionELISAmonoclonal antibodiestuberculosis

Identifiers

PMID31015327
PMCPMC6479003
OpenAlexW2940848581

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.