ArticleBMJ case reports2019
Takotsubo cardiomyopathy secondary to haemophagocytic lymphohistiocytosis in HIV patients: a comprehensive review.
Article in BMJ case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 7 citations in OpenAlex.
- Takotsubo Cardiomyopathy Due to Diffuse Large B-Cell Lymphoma-Associated Hemophagocytic Lymphohistiocytosis.JACC. Case reports · 2025Article
- Hemophagocytic Lymphohistiocytosis and Pancreatic Cancer: A Rare Association.Journal of community hospital internal medicine perspectives · 2023Article
- A Systematic Review Exploring the Effect of Human Immunodeficiency Virus on Cardiac Diseases.Cureus · 2022Review
- Takotsubo cardiomyopathy after cardiac surgery: A case-series and systematic review of literature.Frontiers in cardiovascular medicine · 2022Article
- Haemophagocytic lymphohistiocytosis (HLH)-associated stress cardiomyopathy secondary to autoimmune conditions successfully treated with anakinra.BMJ case reports · 2021Article
- Macrophage Activation Led Acute Heart Failure Managed Successfully with Immunosuppression.Journal of blood medicine · 2021Article
- Echoes of a Cytokine Storm: HLH-Associated Bi-Ventricular Failure in a Young Woman with Lupus - A Case Report.Nigerian medical journal : journal of the Nigeria Medical AssociationReview
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Haemophagocytic lymphohistiocytosis (HLH) is an immune dysregulation disorder with variable presentations and non-specific features making it extremely difficult to diagnose early in the clinical course. Here, we are presenting a case of a young man who presented in cardiogenic shock with findings of anterolateral wall ischaemia on ECG. Echocardiography findings were consistent with takotsubo cardiomyopathy (TCM). Cardiac catheterisation showed clean coronary arteries and pulmonary artery pressure measurements showed high output cardiac failure. After extensive workup, the patient was diagnosed with HLH. In spite of aggressive supportive and definitive therapy, he eventually died due to a complicated clinical course. We did a comprehensive literature review and found that this is the first reported case of HLH presenting as TCM as the initial clinical manifestation.
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Registered trials
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