Evidence map›Paper›PMID 31014776›Full record

ArticleBiological psychology2019

Cold parenting is associated with cellular aging in offspring: A retrospective study.

R Knutsen, V Filippov, S F Knutsen, G E Fraser, J Lloren, D Juma, P Duerksen-Hughes

Open access · greenAbstract read
In one paragraph

Article in Biological psychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

R KnutsenCenter for Nutrition, Healthy Lifestyle and Disease Prevention, School of Public Health, Loma Linda University, Loma Linda, CA 92350, United States. Electronic address: rknutsen@llu.edu.
V FilippovDepartment of Basic Science, School of Medicine, Loma Linda University, Loma Linda, CA 92350, United States.
S F KnutsenCenter for Nutrition, Healthy Lifestyle and Disease Prevention, School of Public Health, Loma Linda University, Loma Linda, CA 92350, United States; Adventist Health Study-2, School of Public Health, Loma Linda University, Loma Linda, CA 92350, United States.
G E FraserCenter for Nutrition, Healthy Lifestyle and Disease Prevention, School of Public Health, Loma Linda University, Loma Linda, CA 92350, United States; Adventist Health Study-2, School of Public Health, Loma Linda University, Loma Linda, CA 92350, United States.
J LlorenAdventist Health Study-2, School of Public Health, Loma Linda University, Loma Linda, CA 92350, United States.
D JumaCenter for Nutrition, Healthy Lifestyle and Disease Prevention, School of Public Health, Loma Linda University, Loma Linda, CA 92350, United States.
P Duerksen-HughesDepartment of Basic Science, School of Medicine, Loma Linda University, Loma Linda, CA 92350, United States.
Loma Linda University · US

Funding

CANCER EPIDEMIOLOGY IN ADVENTISTS--A LOW RISK GROUPR01CA094594 · NCI · LOMA LINDA UNIVERSITY · PI FRASER, GARY E. · 2001 to 2008
$18.0M
Plant-based diets and risk of cancerU01CA152939 · NCI · LOMA LINDA UNIVERSITY · PI FRASER, GARY E. · 2011 to 2015
$5.7M
NCI NIH HHS R01 CA094594NCI NIH HHS U01 CA152939
6 · The paper itself

Abstract

backgroundEarly life stress is a known risk factor for diseases and premature death. We tested whether parenting style impacts telomere length (TL), a cellular aging biomarker.

methodsInformation on parents' style of parenting was obtained from 199 participants in the Adventist Health Study-1 (AHS-1) who 27+ years later also enrolled in the AHS-2 where blood was collected for relative TL (rTL) assessment.

resultsSubjects describing their mothers' parenting style as cold had on average 25% smaller rTL compared to subjects not reporting a cold mother (1.89 vs 2.53). This association was greatest among those with less education, and those who stayed overweight/obese or put on weight during follow-up.

conclusionsThese results support previous findings that early life stress may have health implications by promoting cellular aging, and expands these stressors to include cold parenting during an individuals' formative years. Higher education and normal weight seem to provide some resilience.

Indexed as

AdultCellular SenescenceFemaleHumansMaleMothersObesityParentingParentsRetrospective StudiesRisk FactorsStress, PsychologicalTelomereAdventist Health StudyCohort studyCold parentingEarly life stressEpigeneticsTelomeres

Identifiers

PMID31014776
PMCPMC6774617
OpenAlexW2937763852

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.