ArticleJournal of studies on alcohol and drugs2019
Drug-Induced Craving for Methamphetamine Is Associated With Neural Methamphetamine Cue Reactivity.
Article in Journal of studies on alcohol and drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Oral and Long-acting Injectable Aripiprazole in Severe Mental Illness and Substance Use Disorder Comorbidity: An Updated Systematic Review.Current neuropharmacology · 2025Pooled it
- Are There Neural Overlaps of Reactivity to Illegal Drugs, Tobacco, and Alcohol Cues? With Evidence From ALE and CMA.Frontiers in psychiatry · 2022Pooled it
- Effects of cytidine-5'-diphosphate choline on gray matter volumes in methamphetamine-dependent patients: A randomized, double-blind, placebo-controlled study.Journal of psychiatric research · 2021Trial
- Electrophysiology and Functional Magnetic Resonance Imaging of Cue Craving: Potential Biomarkers for Therapeutic Neuromodulation in Addiction.Biological psychiatry global open science · 2026Review
- The Impaired Response Inhibition and Salience Attribution Model of Drug Addiction: Recent Neuroimaging Evidence and Future Directions.Annual review of psychology · 2026Review
- Altered dynamic reconfiguration of brain functional networks during gaming and deprivation in individuals with internet gaming disorder.Journal of behavioral addictions · 2025Article
- Characterization of serum and brain cytokine levels following prolonged binge-like methamphetamine self-administration and cued methamphetamine seeking.Journal of neuroimmunology · 2025Article
- Amygdala Network Dynamics During Drug Cue Processing in Methamphetamine Use Disorder.Basic and clinical neuroscience · 2025Article
- Transcranial magnetic stimulation for methamphetamine use disorder: A scoping review within the neurocircuitry model of addiction.Psychiatry research · 2024Article
- Psychometric properties of the Turkish version of the Amphetamine Withdrawal Questionnaire Version 2 in patients with methamphetamine use.Dusunen adam : Bakirkoy Ruh ve Sinir Hastaliklari Hastanesi yayin organi · 2024Article
- Methamphetamine dependence in Australia-why is 'ice' (crystal meth) so addictive?Psychiatry, psychology, and law : an interdisciplinary journal of the Australian and New Zealand Association of Psychiatry, Psychology and Law · 2024Article
- Temporally dynamic neural correlates of drug cue reactivity, response inhibition, and methamphetamine-related response inhibition in people with methamphetamine use disorder.Scientific reports · 2022Article
- Theta-Burst Stimulation Combined With Virtual-Reality Reconsolidation Intervention for Methamphetamine Use Disorder: Study Protocol for a Randomized-Controlled Trial.Frontiers in psychiatry · 2022Article
- Altered patterns of fractional amplitude of low-frequency fluctuation and regional homogeneity in abstinent methamphetamine-dependent users.Scientific reports · 2021Article
- Modulation of Methamphetamine-Related Attention Bias by Intermittent Theta-Burst Stimulation on Left Dorsolateral Prefrontal Cortex.Frontiers in cell and developmental biology · 2021Article
- The therapeutic effects of methylphenidate and matrix-methylphenidate on addiction severity, craving, relapse and mental health in the methamphetamine use disorder.Substance abuse treatment, prevention, and policy · 2020Article
- A Scoping Review on Cue Reactivity in Methamphetamine Use Disorder.International journal of environmental research and public health · 2020Article
- An electroencephalography connectome predictive model of craving for methamphetamine.International journal of clinical and health psychology : IJCHPArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveDrug craving serves as the major motivator to propagate drug use and is thought to elicit relapse in abstinent individuals. Although craving for methamphetamine has been investigated using both laboratory and neuroimaging methodologies, the relationship between drug-induced craving and neural responses to methamphetamine cues has yet to be explored. Therefore, the present study investigated whether methamphetamine-induced craving responses in the laboratory were associated with neural response to methamphetamine cues.
methodNon-treatment-seeking individuals with methamphetamine use disorder (n = 15) completed two sessions, one in the laboratory where they underwent a methamphetamine infusion, and one in the magnetic resonance imaging scanner where they viewed methamphetamine cues. Participants reported their craving for methamphetamine over the course of the laboratory session. Analyses examined the association between peak ratings of methamphetamine-induced craving and neural activation to methamphetamine cues.
resultsIn individuals with a methamphetamine use disorder, methamphetamine-induced craving was positively associated with neural methamphetamine cue reactivity in the precuneus, putamen, and ventromedial prefrontal cortex (Z > 2.3, p < .05).
conclusionsThere is a shared neurobiology underlying cue- and drug-induced craving in individuals with methamphetamine use disorder. Treatments that disrupt this circuitry may decrease craving and help prevent relapse.
Indexed as
Identifiers
31014470PMC6489542W2940745891What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.