Evidence map›Paper›PMID 31014404›Full record

ArticleInternational psychogeriatrics2020

Functional deficits and other psychiatric associations with abnormal scores on the Montreal Cognitive Assessment (MoCA) in older HIV-infected patients.

James A Bourgeois, Malcolm John, Roland Zepf, Meredith Greene, Steven Frankel, Nancy A Hessol

Open access · diamondAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in International psychogeriatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

James A BourgeoisBaylor Scott & White Health, Central Texas Division, College of Medicine, Texas A&M University Health Science Center, Temple, TX, USA.
Malcolm JohnDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA.
Roland ZepfDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA.
Meredith GreeneDepartment of Medicine, Division of Geriatrics, University of California San Francisco, San Francisco, CA, USA.
Steven FrankelDepartment of Psychiatry, University of California San Francisco, San Francisco, CA, USA.
Nancy A HessolDepartment of Clinical Pharmacy, University of California San Francisco, San Francisco, CA, USA.
University of California, San Francisco · USBaylor Scott & White Health · US

Funding

RESEARCH TRAINING IN GERIATRIC MEDICINET32AG000212 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Alexander Keliimoeanu Smith · 1991 to 2026
$7.7M
UCLA Implementation Science and Substance Use Research and Education (ISSURE) ProgramR25DA035692 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TIMOTHY W FONG, GAIL E. WYATT · 2013 to 2026
$3.9M
NIA NIH HHS T32 AG000212NIDA NIH HHS R25 DA035692
6 · The paper itself

Abstract

objectiveThe authors assessed the association of physical function, social variables, functional status, and psychiatric co-morbidity with cognitive function among older HIV-infected adults.

designFrom 2012-2014, a cross-sectional study was conducted among HIV-infected patients ages 50 or older who underwent comprehensive clinical geriatric assessment.

settingTwo San Francisco HIV clinics.

participants359 HIV-infected patients age 50 years or older. MEASUREMENTS: Unadjusted and adjusted Poisson regression measured prevalence ratios and 95% confidence intervals for demographic, functional and psychiatric variables and their association with cognitive impairment using a Montreal Cognitive Assessment (MoCA) score < 26 as reflective of cognitive impairment.

resultsThirty-four percent of participants had a MoCA score of < 26. In unadjusted analyses, the following variables were significantly associated with an abnormal MoCA score: born female, not identifying as homosexual, non-white race, high school or less educational attainment, annual income < $10,000, tobacco use, slower gait speed, reported problems with balance, and poor social support. In subsequent adjusted analysis, the following variables were significantly associated with an abnormal MoCA score: not identifying as homosexual, non-white race, longer 4-meter walk time, and poor social support. Psychiatric symptoms of depressive, anxiety, and post-traumatic stress disorders did not correlate with abnormal MoCA scores.

conclusionsCognitive impairment remains common in older HIV-infected patients. Counter to expectations, co-morbid psychiatric symptoms were not associated with cognitive impairment, suggesting that cognitive impairment in this sample may be due to neurocognitive disorders, not due to other psychiatric illness. The other conditions associated with cognitive impairment in this sample may warrant separate clinical and social interventions to optimize patient outcomes.

Indexed as

Mental Status and Dementia TestsAgedAged, 80 and overAIDS Dementia ComplexCognitive DysfunctionCross-Sectional StudiesFemaleGeriatric AssessmentHIV InfectionsHumansMaleMiddle AgedPsychometricsSelf ReportSensitivity and Specificityfunctional assessmentHIVHIV-associated neurocognitive disorderMontreal Cognitive Assessment (MoCA)psychiatric co-morbidity

Identifiers

PMID31014404
PMCPMC7781491
OpenAlexW2941634960

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.