Evidence map›Paper›PMID 31014390›Full record

ArticleInfectious diseases of poverty2019

Molluscicidal effectiveness of Luo-Wei, a novel plant-derived molluscicide, against Oncomelania hupensis, Biomphalaria alexandrina and Bulinus truncatus.

Tie-Wu Jia, Wei Wang, Le-Ping Sun, Shan Lv, Kun Yang, Neng-Min Zhang, Xi-Bao Huang, Jian-Bing Liu, Han-Cheng Liu, Rui-Hua Liu and 5 more

Erratum issuedAbstract read
In one paragraph

Article in Infectious diseases of poverty, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Molluscicidal Activity ofJournal of parasitology research · 2026
    Article
  3. Article
  4. Biocontrol potential ofParasite epidemiology and control · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Resistance ofJournal of parasitology research · 2020
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Tie-Wu JiaNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, 200025, China.
Wei WangKey Laboratory of National Health Commission on Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasites and Vector Control Technology, Jiangsu Institute of Parasitic Diseases, Wuxi, 214064, China.
Le-Ping SunKey Laboratory of National Health Commission on Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasites and Vector Control Technology, Jiangsu Institute of Parasitic Diseases, Wuxi, 214064, China.
Shan LvNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, 200025, China.
Kun YangKey Laboratory of National Health Commission on Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasites and Vector Control Technology, Jiangsu Institute of Parasitic Diseases, Wuxi, 214064, China.
Neng-Min ZhangHubei Jinhaichao Science & Technology Co., Ltd, Wuhan, 430206, China.
Xi-Bao HuangHubei Provincial Center for Disease Control and Prevention, Wuhan, 430079, China.
Jian-Bing LiuHubei Provincial Center for Disease Control and Prevention, Wuhan, 430079, China.
Han-Cheng LiuHubei Provincial Center for Disease Control and Prevention, Wuhan, 430079, China.
Rui-Hua LiuSchool of Chemistry and Chemical Engineering, Wuhan Textile University, Wuhan, 430200, China.
Fathia A GawishDepartment of Medical Malacology, Theodor Bilharz Research Institute (TBRI), Imbaba, Giza, 12411, Egypt.
Mohamed R HabibDepartment of Medical Malacology, Theodor Bilharz Research Institute (TBRI), Imbaba, Giza, 12411, Egypt.
Mohamed A El-EmamDepartment of Medical Malacology, Theodor Bilharz Research Institute (TBRI), Imbaba, Giza, 12411, Egypt.
Charles H KingCenter for Global Health and Diseases, Case Western Reserve University, Cleveland, OH, USA. chk@case.edu.
Xiao-Nong ZhouNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, 200025, China. xiaonongzhou1962@gmail.com.

Funding

Jiangsu Provincial Health and Family Planning Commission QNRC2016621National S & T Major Program 2012ZX10004-220National Science and Technology Pillar Program 2009BAI78B04National Science and Technology Pillar Program 2009BAI78B07Science and Technology Commission of Shanghai Municipality (CN) 11XD1405400Wuxi Municipal Bureau of Science and Technology CSE31N1730
6 · The paper itself

Abstract

backgroundControl of snail intermediate hosts has been proved to be a fast and efficient approach for interrupting the transmission of schistosomiasis. Some plant extracts have shown obvious molluscicidal activity, and a new compound Luo-Wei, also named tea-seed distilled saponin (TDS), was developed based on the saponins extracted from Camellia oleifera seeds. We aimed to test the molluscicidal activity of 4% TDS against the intermediate host snails in China and Egypt, and evaluate its environmental safety to non-target organisms.

methodsIn the laboratory, Oncomelania hupensis, Biomphalaria alexandrina and Bulinus truncatus were exposed to 4% TDS, and the median lethal concentration (LC

resultsIn the laboratory, the LC

conclusions4% TDS is active against O. hupensis, B. alexandrina and B. truncatus under laboratory and field conditions, and it may be a candidate molluscicide of plant origin.

Indexed as

AnimalsBiomphalariaBulinusChinaEgyptLethal Dose 50MolluscacidesPlant ExtractsQuailSchistosomaSchistosomiasisSnailsToxicity TestsMolluscacidesPlant ExtractsBiomphalaria alexandrinaBulinus truncatusLuo-WeiMolluscicidal activityOncomelania hupensisPlant-derived molluscicideSchistosomiasis

Identifiers

PMID31014390
PMCPMC6480903

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.