Evidence map›Paper›PMID 31014382›Full record

Trial reportJournal of orthopaedic surgery and research2019

Platelet-rich plasma versus lidocaine as tenotomy adjuvants in people with elbow epicondylopathy: a randomized controlled trial.

Jose Ignacio Martin, Leire Atilano, Josu Merino, Igor Gonzalez, Gotzon Iglesias, Luis Areizaga, Paola Bully, Gonzalo Grandes, Isabel Andia

2 registry-linked trialsOpen access · goldAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of orthopaedic surgery and research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01945528 phase3completednot on this map

Pilot Randomized Controlled Trial to Evaluate Safety and Efficacy of Percutaneous Needle Tenotomy With Platelet Rich Plasma (Leukocyte Depleted)in Epicondylitis

TypeinterventionalSponsorJose Ignacio MartinRan2014 to 2018Enrolled86ConditionsEpicondylitisArmsUS-guided tenotomy with PRP, US-guided tenotomy with lidocaine
NCT03987256 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Tennis Elbow, Randomized Study: Needling With and Without Platelet-rich Plasma After Failure of Up-to-date Rehabilitation

TypeinterventionalSponsorAdrien SchwitzguebelRan2020 to 2022Enrolled58ConditionsTennis Elbow, PRP, Tendinopathy, TendinosisArmsInitial rehabilitation protocol, Needling with PRP, Needling with saline solution
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
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  4. Trial
  5. The Association Between ThreeInternational journal of molecular sciences · 2025
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  15. Current Trends for Treating Lateral Epicondylitis.Clinics in shoulder and elbow · 2019
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jose Ignacio MartinInterventional Sonography, Department of Radiology, Cruces University Hospital, Barakaldo, Spain.
Leire AtilanoInterventional Sonography, Department of Radiology, Cruces University Hospital, Barakaldo, Spain.
Josu MerinoRegenerative Medicine, BioCruces Health Research Institute, Cruces University Hospital, 48903, Barakaldo, Spain.
Igor GonzalezRegenerative Medicine, BioCruces Health Research Institute, Cruces University Hospital, 48903, Barakaldo, Spain.
Gotzon IglesiasInterventional Sonography, Department of Radiology, Cruces University Hospital, Barakaldo, Spain.
Luis AreizagaRegenerative Medicine, BioCruces Health Research Institute, Cruces University Hospital, 48903, Barakaldo, Spain.
Paola BullyPrimary Care Research Unit of Bizkaia (Basque Healthcare Service), BioCruces Health Research Institute, Bilbao, Spain.
Gonzalo GrandesPrimary Care Research Unit of Bizkaia (Basque Healthcare Service), BioCruces Health Research Institute, Bilbao, Spain.
Isabel AndiaRegenerative Medicine, BioCruces Health Research Institute, Cruces University Hospital, 48903, Barakaldo, Spain. isabel.andiaortiz@osakidetza.eus.ORCID http://orcid.org/0000-0003-0607-4767
BioCruces Health research Institute · ES

Funding

Instituto de Salud Carlos III (ES) PI13/01707
6 · The paper itself

Abstract

objectivesTo determine the efficacy of platelet-rich plasma (PRP) compared to lidocaine as a tenotomy adjuvant for people with elbow tendinopathy.

methodsOur study was a parallel-group, double-blind, randomized trial involving 71 patients with recalcitrant elbow tendinopathy who received two sessions of ultrasound-guided tenotomy with either PRP or lidocaine in a tertiary public hospital. The primary end point was the percentage of patients with an improvement exceeding 25% reduction in disability (Spanish version of the Disabilities of the Arm, Shoulder and Hand questionnaires-DASH-E) at 6 and 12 months; the secondary outcome was the percentage of patients exceeding 25% reduction in pain (VAS-P).

resultsThere was no evidence of significant differences in the proportion of patients who experienced clinically relevant improvements. After 6 months, 18 patients (78.59%) in the lidocaine group and 19 patients (73.08%) in the PRP group showed improved function above 25% (unadjusted odds ratio, 0.90; 95% confidence interval [CI], 0.90 (0.17 to 4.60)); 21 patients (72.21%) in the lidocaine group versus 22 patients (84.62%) in the PRP group achieved more than 25% pain reduction (unadjusted odds ratio, 0.48; 95% CI, 0.10 to 2.37). After 12 months, 17 patients (70.83%) in the lidocaine group versus 19 patients (76%) in the PRP group had improved function (unadjusted odds ratio, 0.71; 95% CI, 0.13 to 3.84), and 19 patients (76%) in the lidocaine group versus 20 patients (90.91%) in the PRP group had improved pain above 25% (unadjusted odds ratio, 0.35; 95% CI, 0.06 to 2.51). Hypercholesterolemia and baseline vascularization influenced outcomes. There were no differences between groups in the adjusted odds ratios.

conclusionPRP results in similar improvements to those obtained with lidocaine. Selecting patients according to their pretreatment status can improve treatment efficacy.

trial registrationNCT01945528 , EudraCT 2013-000478-32. Registered 18 August 2013, enrolment of the first participant 10 March 2014.

Indexed as

Platelet-Rich PlasmaAdultAnesthetics, LocalDouble-Blind MethodFemaleHumansLidocaineMaleMiddle AgedTennis ElbowTenotomyUltrasonography, InterventionalAnesthetics, LocalLidocaineElbow tendinopathyEpicondylitisFunctionLateralMedialPainPlatelet-rich plasmaRandomized controlled studySonographyTenotomy

Identifiers

PMID31014382
PMCPMC6480601
OpenAlexW2945824897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.